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Journals / Sağlık Bilimleri Dergisi / 2004 / Cilt: 13 - Sayı: 2

Effects of propolis and mitomycin-C on micronucleus in tissue cultures of bladder cancer

Mesane kanserli doku kültürlerindeki mikronükleus üzerine propolis ve mitomisin-C'nin etkileri

Halil Erhan EROĞLU
Atilla TATLIŞEN
Yusuf ÖZKUL
Pages
15–20
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Propolis and mitomycin-C increased the micronucleus rate of the cell when compared to untreated control (p

📌 3 Key Takeaways

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Objective & Hypothesis:Summary : In this study, we have tested the mutagenic effects of mitomycin-C (MMC) and propolis on transitional carcinoma cell cultures.
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Key Findings & Data:In this study, 0.1 ml propolis (8 g propolis + 8% 15 ml L-Lysin), 1.6 µl mitomycin-C (0.1 mg/ml) and 0.1 ml L-Lysin (80 mg L-Lysin + 1 ml distilled water) were added to cancer tissue cultures and the effects of these solutions on the micronucleus (MN) rate were evaluated.
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Conclusion & Impact:Propolis and mitomycin-C increased the micronucleus rate of the cell when compared to untreated control (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Summary : In this study, we have tested the mutagenic effects of mitomycin-C (MMC) and propolis on transitional carcinoma cell cultures. Tissue samples were obtained from transurethral resection (TUR) tissue of patients with superficial bladder cancer. In this study, 0.1 ml propolis (8 g propolis + 8% 15 ml L-Lysin), 1.6 µl mitomycin-C (0.1 mg/ml) and 0.1 ml L-Lysin (80 mg L-Lysin + 1 ml distilled water) were added to cancer tissue cultures and the effects of these solutions on the micronucleus (MN) rate were evaluated. Propolis and mitomycin-C increased the micronucleus rate of the cell when compared to untreated control (p

Özet

Özet : Bu çalışmada yüzeyel mesane kanserli hastaların transüretral rezeksiyon (TUR) doku örneklerinden hazırlanan tranzisyonel karsinom hücre kültürlerinde mitomisin-C (MMC) ve propolisin mutagenik etkilerine bakıldı. Çalışmamızda mesane kanserli doku kültürlerine 0.1 ml propolis (8 g propolis + %8’lik 15 ml L-Lizin), 1.6 µl mitomisin-C (0.1 mg/ml) ve 0.1 ml L-Lizin (80 mg L-Lizin + 1 ml distile su) ilave edilerek, mikronükleus üzerine etkileri değerlendirildi. Sonuçlarımız propolis ve mitomisin- C’nin kontrol grubuna hücrelerdeki mikronükleus (MN) oranını arttırdığını göstermektedir (p

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Cite This Article

EROĞLU, H. E., TATLIŞEN, A., ÖZKUL, Y. (2022). Effects of propolis and mitomycin-C on micronucleus in tissue cultures of bladder cancer. Sağlık Bilimleri Dergisi, Cilt: 13 - Sayı: 2, 15–20. https://ajindex.com/articles/590218

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