Associations Between Olfactory Impairment and Cognitive Functions in Patients with Parkinson Disease

The Unified Parkinson’s Disease Rating Scale (UPDRS) andHoehn and Yahr Scale (H&Y Scale) were administered to all subjects.Butanol threshold test and Sniffin’Sticks test were used to assess olfaction.The Mini Mental State Examination (MMSE) and Clock Drawing Test(CDT) and Stroop Color Word Test (SCWT) were used to assess cognition.Results: The Sniffin’Sticks test scores were significantly lower in theParkinson group in comparison to the control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Olfactory impairment and cognitive impairment arecommon non-motor symptoms in Parkinson’s disease (PD).

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Key Findings & Data:The associations between olfactory loss andcognition in PD are evaluated in this study.Methods: 31 patients with PD and 31 healthy subjects were includedin this study.

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Conclusion & Impact:The Unified Parkinson’s Disease Rating Scale (UPDRS) andHoehn and Yahr Scale (H&Y Scale) were administered to all subjects.Butanol threshold test and Sniffin’Sticks test were used to assess olfaction.The Mini Mental State Examination (MMSE) and Clock Drawing Test(CDT) and Stroop Color Word Test (SCWT) were used to assess cognition.Results: The Sniffin’Sticks test scores were significantly lower in theParkinson group in comparison to the control group (p

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Introduction: Olfactory impairment and cognitive impairment arecommon non-motor symptoms in Parkinson’s disease (PD). Olfactoryimpairment may be present even many years before the main symptomsof the disease develop. The associations between olfactory loss andcognition in PD are evaluated in this study.Methods: 31 patients with PD and 31 healthy subjects were includedin this study. The Unified Parkinson’s Disease Rating Scale (UPDRS) andHoehn and Yahr Scale (H&Y Scale) were administered to all subjects.Butanol threshold test and Sniffin’Sticks test were used to assess olfaction.The Mini Mental State Examination (MMSE) and Clock Drawing Test(CDT) and Stroop Color Word Test (SCWT) were used to assess cognition.Results: The Sniffin’Sticks test scores were significantly lower in theParkinson group in comparison to the control group (p

Özet

Amaç: Koku kaybı ve kognitif bozukluk Parkinson hastalığında (PH) sıklıkla görülen non-motor semptomlardır. Hastalığa ait ana semptomlar ortaya çıkmadan yıllar öncesinde bile koku kaybı görülebilir. Bu çalışmada PH’da koku kaybı ile kognisyon arasındaki ilişki incelenmiştir. Yöntem: Çalışmaya 31 Parkinson hastası, 31 sağlıklı birey dahil edildi. Tüm hastalara nöroloji uzmanı tarafından Birleşik Parkinson Hastalığı Değerlendirme Ölçeği (BPHDÖ) ve Hoehn Yahr evrelemesi (HYE) yapıldı. Koku duyusunu değerlendirmek amacıyla butanol threshold test ve sniffin sticks test kullanıldı. Kongnisyonu değerlendirmek amacıyla standardize minimental test (SMMT), saat çizme testi (SÇT) ve stroop testi yapıldı. Bulgular: Parkinson grubunda Sniffin’Sticks testi puanları kontrol grubuna göre anlamlı derecede düşüktü (p

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Cite This Article

TAYMUR, İ., BUDAK, E., SIĞIRLI, D., PEKEL, N. B., YILDIZ, D., SEFEROĞLU, M., ÖZMEN, S., ÇAPKUR, Ç., GÜNEŞ, A. (2022). Associations Between Olfactory Impairment and Cognitive Functions in Patients with Parkinson Disease. Nöropsikiyatri Arşivi, Cilt: 57 - Sayı: 3, 216–221. https://ajindex.com/articles/584640

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