Journals / Kolon ve Rektum Hastalıkları Dergisi / 2008 / Cilt: 18 - Sayı: 1

Management of locally recurrent rectal cancer

Rektum kanserinde lokal nükse yaklaşım

Pages
1–6
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In recent studies, it has been shown that survival will be extended with agressive multimodality treatment methods.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The most important factor for obtaining long-term local control and survival is R0 resection for rectal cancer.
📊
Key Findings & Data:Radical surgical treatment with adjuvant therapy may lead to an improved salvage rate.
💡
Conclusion & Impact:In recent studies, it has been shown that survival will be extended with agressive multimodality treatment methods.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The most important factor for obtaining long-term local control and survival is R0 resection for rectal cancer. Locoregional relapse may develop in rectal cancer, despite radical surgery. Local pelvic recurrence has been usually associated with morbidity and cancer-related death on the basis of performed procedure. The management of these patients is particularly challenging. Surgical resection is the mainstay of treatment for those with a local recurrence. In surgical treatment for local recurrence, surgeon-related factors are crucial. Careful patient selection according to the pattern of recurrence, area of invasion and presence of symptoms is important for successful curative surgery. Radical surgical treatment with adjuvant therapy may lead to an improved salvage rate. In recent studies, it has been shown that survival will be extended with agressive multimodality treatment methods.

Özet

Rektum kanserinde uzun dönem lokal kontrol ve sağkalımı sağlamak için en önemli faktör R0 rezeksiyondur. Radikal cerrahiye rağmen lokorejyonel nüks gelişebilir. Rezeksiyon sonrası gelişen nüks genellikle morbidite veya ölümle sonuçlanır. Bu hastaların tedavisi oldukça zordur. Cerrahi rezeksiyon, lokal nükste başlıca tedavi seçeneğidir. Lokal nüksün etkin cerrahi tedavisinde cerrah önemli bir yer teşkil eder. Etkin ve başarılı küratif cerrahi için hastanın semptomları, nüksün boyutu ve invazyon alanı önem taşır. Radikal cerrahi tedaviyle birlikte adjuvan tedavi yüksek iyileşme oranı sağlar. Son çalışmalarda, lokal nüks gelişen rektum kanserlerinde agresif multi-disipliner tedavi yöntemleriyle sağkalım oranlarının artırılabildiği gösterilmiştir.

🔖

Cite This Article

BACA, B., KARAHASANOĞLU, T. (2022). Management of locally recurrent rectal cancer. Kolon ve Rektum Hastalıkları Dergisi, Cilt: 18 - Sayı: 1, 1–6. https://ajindex.com/articles/575437

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Van den Brink M, Stiggelbout AM, van den Hout WB, et al. Clinical nature and prognosis of locally recurrent rectal cancer after total mesorectal excision with or without preoperative radiotherapy. J Clin Oncol 2004;22:3958-64
  2. Heald RJ. Total mesorectal excision is optimal surgery for rectal cancer: a Scandinavian consensus. Br J Surg 1995;82:1297-1299
  3. Kapiteijn E, Marijnen CA, Nagtegaal ID, et al. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 2001;345:638-46
  4. McCall JL, Cox MR, Wattchow DA. Analysis of local recurrence rates after surgery alone for rectal cancer. Int J Colorectal Dis 1995;10:126-32
  5. Stearns MW. Diagnosis and management of recurrent pelvic malignancy following combined abdominoperineal resection. Dis Colon Rectum 1980;23:359-61
  6. Pacini P, Cionini L, Pirtoli L, et al. Symptomatic recurrences of carcinoma of the rectum and sigmoid. The influence of radiotherapy on the quality of life. Dis Colon Rectum 1986; 29:865-8
  7. Radice E, Dozois RR. Locally recurrent rectal cancer. Dig Surg 2001;18:355-62
  8. Moore HG, Harrison LE, Guillem J. Cancer of the rectum; follow-up and management of local recurrence. In Fazio VW, Church JM, Delaney CP (eds), Current therapy in colon and rectal surgery. Elsevier Mosby,2005;185-90
  9. Sagar P. Reoperative surgery for recurrent rectal cancer. In: Longo WE, Northover J, eds. Reoperative colon and rectal surgery. London: Martin Dunitz, 2003: 221-51
  10. Heald RJ, Ryall RD. Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1986;1:1479-82
  11. Ueno H, Mochizuki H, Hashiguchi Y, et al. Prognostic determinants of patients with lateral nodal involvement by rectal cancer. Ann Surg 2001;234:190-7
  12. Hida J, Yasutomi M, Fujimoto K, et al. Does lateral lymph node dissection improve survival in rectal carcinoma? Examination of node metastases by the clearing method. J Am Coll Surg 1997;184:475-80
  13. Moriya Y, Sugihara K, Akasu T, et al. Importance of extended lymphadenectomy with lateral node dissection for advanced lower rectal cancer. World J Surg 1997;21:728-32
  14. Pezim ME, Nicholls RJ. Survival after high or low ligation of the inferior mesenteric artery during curative surgery for rectal cancer. Ann Surg 1984;200:729-33
  15. Adam IJ, Mohamdee MO, Martin IG, et al. Role of circumferential margin involvement in the local recurrence of rectal cancer. Lancet 1994;344:707-11
  16. Wilson SM, Beahrs OH. The