Journals / Klimik Dergisi / 2011 / Cilt: 24 - Sayı: 2

Evaluation of in vitro antibiotic sensitivity of enterococci isolated from urine samples

İdrar örneklerinden izole edilen enterokokların in vitro antibiyotik direnç oranlarının değerlendirilmesi

Pages
105–107
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: Although no enterococcal strain with glycopeptide resistance was isolated, special attention should be paid to high-level aminoglycoside resistance in treating enterococcal infections

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is evaluation of in vitro sensitivity and resistance rate of 293 enterococcal strains isolated from the urine samples of patients with a history suggestive of urinary tract infection in our hospital.
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Key Findings & Data:Results: Resistance rates of enterococcal strains to penicillin, ampicillin, erythromycin, tetracycline, levofloxacin, and ciprofloxacin were found to be 85.4% (135/158), 35.2% (92/261), 69.6% (155/223), 28.4% (35/123), 28.6% (36/126), 53.1% (110/207), respectively.
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Conclusion & Impact:Conclusions: Although no enterococcal strain with glycopeptide resistance was isolated, special attention should be paid to high-level aminoglycoside resistance in treating enterococcal infections
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study is evaluation of in vitro sensitivity and resistance rate of 293 enterococcal strains isolated from the urine samples of patients with a history suggestive of urinary tract infection in our hospital. Methods: Identification was performed by conventional methods. Antimicrobial susceptibility was determined by disk diffusion method in accordance with Clinical Laboratory Standards Institute (CLSI). Results: Resistance rates of enterococcal strains to penicillin, ampicillin, erythromycin, tetracycline, levofloxacin, and ciprofloxacin were found to be 85.4% (135/158), 35.2% (92/261), 69.6% (155/223), 28.4% (35/123), 28.6% (36/126), 53.1% (110/207), respectively. A high level resistance rate was found against aminoglycosides, namely 51.2% (139/271) for gentamicin (120 mg) and 60.6% (89/147) for streptomycin (300 mg). Conclusions: Although no enterococcal strain with glycopeptide resistance was isolated, special attention should be paid to high-level aminoglycoside resistance in treating enterococcal infections

Özet

Amaç: Hastanemize başvuran ve idrar yolu infeksiyonu düşünülen hastaların idrar örneklerinden izole edilen 293 enterokok suşunun antibiyotiklere in vitro duyarlılıklarının irdelenmesi amaçlanmıştır. Yöntemler: Üreyen suşların idantifikasyonu konvansiyonel yöntemlerle yapılmıştır. Antimikrobiyal duyarlılıkları Clinical Laboratory Standards Institute (CLSI) kriterlerine göre disk difüzyon yöntemiyle belirlenmiştir. Bulgular: Enterokok suşlarında penisiline %85.4 (135/158), ampisiline %35.2 (92/261), eritromisine %69.6 (155/223), tetrasikline %28.4 (35/123), levofloksasine %28.6 (36/126), siprofloksasine %53.1 (110/207) oranında direnç saptanırken; aminoglikozidlere yüksek düzeyde direnç oranları gentamisin (120 μg) için %51.2 (139/271), streptomisin (300 μg) için %60.6 (89/147) olarak belirlenmiştir. Sonuçlar: Glikopeptide dirençli enterokoka rastlanmamakla birlikte, enterokok infeksiyonlarının tedavisinde yüksek düzey aminoglikozid direnç oranlarının göz önünde bulundurulmasına dikkat çekilmiştir.

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Cite This Article

GÜNGÖR, S., KURULTAY, N., YURTSEVER, G. S., KALAYCI, Ö., UZUN, B. (2022). Evaluation of in vitro antibiotic sensitivity of enterococci isolated from urine samples. Klimik Dergisi, Cilt: 24 - Sayı: 2, 105–107. https://ajindex.com/articles/573696

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