Journals / Klimik Dergisi / 2011 / Cilt: 24 - Sayı: 1

Weil s disease: Four cases from Çukurova, Turkey

Weil hastalığı: Çukurova'dan dört olgu bildirimi

Pages
52–56
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Weil s disease should be considered in the differential diagnosis of patients with fever, myalgia, icterus, severe thrombocytopenia, abnormal liver function tests, and renal failure.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Weil s disease is the most serious form of leptospirosis presenting with icterus and renal failure, which is seen in 5-10% of cases.
📊
Key Findings & Data:In this report, four patients with Weil s disease who were followed up in our clinic between 2006 and 2009 were presented.
💡
Conclusion & Impact:Weil s disease should be considered in the differential diagnosis of patients with fever, myalgia, icterus, severe thrombocytopenia, abnormal liver function tests, and renal failure.
🔬Design:Research Article
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

Weil s disease is the most serious form of leptospirosis presenting with icterus and renal failure, which is seen in 5-10% of cases. In this report, four patients with Weil s disease who were followed up in our clinic between 2006 and 2009 were presented. All cases had an acute-onset fever, myalgia, fatigue, abdominal pain, and icterus. Thrombocytopenia, abnormal liver function tests, and increased levels of muscle enzymes and creatinine were detected in all patients. Microscopic agglutination tests were used for diagnosis. While three patients fully recovered, one patient had chronic renal failure as a sequel. Weil s disease should be considered in the differential diagnosis of patients with fever, myalgia, icterus, severe thrombocytopenia, abnormal liver function tests, and renal failure.

Özet

Weil hastalığı, leptospirozun, sarılık ve böbrek yetmezliğiyle seyreden ve olguların %5-10unda görülen en ağır formudur. Bu çalışmada 2006-2009 yılları arasında kliniğimizde Weil hastalığı tanısıyla izlenen dört olgu sunulmuştur. Tüm olgular, akut başlayan ateş, kas ağrısı, halsizlik, karın ağrısı ve sarılık şikayetleriyle başvurmuştur. Hastaların hepsinde trombositopeni, karaciğer fonksiyon testlerinde bozulma, kas enzimlerinde ve kreatinin değerlerinde yükselme saptanmıştır. Hastalığın tanısı mikroskopik aglütinasyon testiyle konulmuştur. Üç olgu şifayla iyileşirken, bir olguda kronik böbrek hastalığı sekel olarak kalmıştır. Ateş, kas ağrısı, sarılık şikayetleriyle başvuran ciddi trombositopeni, karaciğer fonksiyon bozukluğu ve böbrek yetmezliği saptanan olguların ayırıcı tanısında Weil hastalığı da düşünülmelidir.

🔖

Cite This Article

KASAR, M., BOĞA, C., TİMURKAYNAK, F., TURUNÇ, T., DEMİROĞLU, Y. Z. (2022). Weil s disease: Four cases from Çukurova, Turkey. Klimik Dergisi, Cilt: 24 - Sayı: 1, 52–56. https://ajindex.com/articles/652929

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Human Leptospirosis: Guidance for Diagnosis, Surveillance and Control [İnternet]. Geneva, Switzerland: WHO [erişim 25 Mart 2010]. http://whqlibdoc.who.int/hq/2003/WHO_CDS_CSR_ EPH_2002.23.pdf 2.Levett PN. Leptospirosis. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 6th ed. Philadelphia: Elsevier Churchill Livingstone, 2005: 2789-95. 3.Doudier B, Garcia S, Quennee V, Jarno P, Brouqui P. Prognostic factors associated with severe leptospirosis. Clin Microbiol Infect. 2006
  2. 12(4): 299-300. [Crossref] 4.Lau C, Smythe L, Weinstein P. Leptospirosis: an emerging disease in travellers. Travel Med Infect Dis. 2010
  3. 8(1): 33-9. [Crossref] 5.Karande S, Bhatt M, Kelkar A, Kulkarni M, De A, Varaiya A. An observational study to detect leptospirosis in Mumbai, India, 2000. Arch Dis Child. 2003
  4. 88(12): 1070-5. [Crossref] 6.Esen S, Sunbul M, Leblebicioglu H, Eroglu C, Turan D. Impact of clinical and laboratory findings on prognosis in leptospirosis. Swiss Med Wkly. 2004
  5. 134(23-24): 347-52. 7.Saltoğlu N, Aksu HZ, Taşova Y, et al. Leptospirosis: twelve Turkish patients with the Weil syndrome. Acta Med Okayama. 1997
  6. 51(6): 339-42. 8.Turhan V, Polat E, Atasoyu EM, Ozmen N, Kucukardalı Y, Cavuslu S. Leptospirosis in Istanbul, Turkey: a wide spectrum in clinical course and complications. Scand J Infect Dis. 2006
  7. 38(10): 845-52. [Crossref] 9.Gürcüoğlu E, Öztürk Ç, Bayat N, Akalın H. Leptospiroz: Güney Marmara’dan üç olgu. Klimik Derg. 2009
  8. 22(2): 62-5. 10.Durmaz Çetin B, Hasman H, Gündüz A, Seber E. On üç leptospiroz olgusunun değerlendirilmesi. Klimik Derg. 2003
  9. 16(2): 91-4. 11.Özgüneş N, Ceylan N, Sargın F, Polat E. Weil hastalığı: bir olgu sunumu. Klimik Derg. 2003
  10. 16(3): 138-9. 12.Turhan V, Doğru T, Ardıç N, Ağdaş Ş, Özdemir V. Bir olgu nedeniyle anikterik leptospiroz: sıklıkla gözden kaçabilen bir infeksiyon hastalığı. Klimik Derg. 2007
  11. 20(1): 29-31. 13.Karsen H, Karahocagil MK, Sünnetçioğlu M, Yapıcı K, Ekin S. Weil hastalığı: bir olgu sunumu. Klimik Derg. 2008
  12. 21(1): 34-5. 14.Abgueguen P, Delbos V, Blanvillain J, et al. Clinical aspects and prognostic factors of leptospirosis in adults. Retrospective study in France. J Infect. 2008
  13. 57(3): 171-8. [Crossref] 15.Levett PN. Leptospirosis. Clin Microbiol Rev. 2001
  14. 14(2): 296-326. [Crossref] 16.Daher EF, Lima RS, Silva Júnior GB, et al. Clinical presentation of leptospirosis: a retrospective study of 201 patients in a metropolitan city of Bra