Journals / Journal of the Turkish-German Gynecological Association / 2019 / Cilt: 20 - Sayı: 2

Effects of mature cystic teratoma on reproductive health and malignant transformation: A retrospective analysis of 80 cases

Pages
84–88
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In MCT malignant degeneration, mass diameter, complex mass internal structure, and postmenopausal status are important factors. (J Turk Ger Gynecol Assoc 2019; 20: 84-8)

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Objective & Hypothesis:Objective: To examine cases of mature cystic teratoma (MCT) that were diagnosed and treated in our clinic regarding their association with fertility, and to detect the rate of malignant degeneration and the types of malignancies.Material and Methods: Patients who underwent surgery due to adnexal mass between April 2012 and August 2017 and were diagnosed as having MCT were retrospectively examined.
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Key Findings & Data:The mean age of the 80 patients who met the inclusion criteria was 30.60±10.5 years.
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Conclusion & Impact:In MCT malignant degeneration, mass diameter, complex mass internal structure, and postmenopausal status are important factors. (J Turk Ger Gynecol Assoc 2019; 20: 84-8)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To examine cases of mature cystic teratoma (MCT) that were diagnosed and treated in our clinic regarding their association with fertility, and to detect the rate of malignant degeneration and the types of malignancies.Material and Methods: Patients who underwent surgery due to adnexal mass between April 2012 and August 2017 and were diagnosed as having MCT were retrospectively examined. The mean age of the 80 patients who met the inclusion criteria was 30.60±10.5 years. Nine had infertility according to hospital records. Sixty-seven percent of these (n=6) had accompanying endometriosis and MCT was bilateral in 55.5% (n=5). Malignant degeneration was present in 6.25% (n=5), all were monodermal tumors. Malignant degeneration was more common among patients with larger diameter adnexal masses (9.1±2.9 cm) and in those of postmenopausal age. Tumor markers were within the normal range for patients who developed malignancy. Malignant degeneration was not present among infertile patients with endometriosis.Results: Although MCTs do not seem to negatively affect the ovarian reserve, infertility is prominent in patients with concurrent endometriosis. During assessment, concurrent endometriosis should be considered. Imaging findings, large adnexal masses, and postmenopausal period are important for the assessment of MCT concerning malignant degeneration. It should not be overlooked because tumor markers may be normal.Conclusion: MCTs can be present concurrent with endometriomas. In such cases, infertility is more distinct. In MCT malignant degeneration, mass diameter, complex mass internal structure, and postmenopausal status are important factors. (J Turk Ger Gynecol Assoc 2019; 20: 84-8)

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Cite This Article

SAYGILI, U., SAATLİ, H. B., DOĞAN, Ö. E., AVŞAR, H. A., KURT, S. (2022). Effects of mature cystic teratoma on reproductive health and malignant transformation: A retrospective analysis of 80 cases. Journal of the Turkish-German Gynecological Association, Cilt: 20 - Sayı: 2, 84–88. https://ajindex.com/articles/567462

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