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Journals / Medical Network Klinik Bilimler ve Doktor / 2002 / Cilt: 8 - Sayı: 2

Prognostik importance of intraoperative cyst rupture in early stage epithelial ovarian carcinoma

Erken evre epitelyal over karsinomunda intraoperatif kist rüptürünün prognostik önemi

Uğur SAYGILI
Serkan GÜÇLÜ
Cemal POSACI
Meral KOYUNCUOĞLU
Turhan USLU
Oktay ERTEN
Pages
248–251
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

RESULTS: Overall survivals were not different among the three groups (P>0.05).

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTİVE: To investigate of prognostic importance of intraoperative cyst rupture in patients with early stage epithelial ovarian carcinoma MATERIAL AND METHODS: The prognostic influence of intraoperative tumor rupture was examined in 49 patients with stage I malignant ovarian carcinoma were treated between 1990 and 1998.
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Key Findings & Data:Group 1 included 14 patients with stage Ia, group 2 included 19 patients with stage Ic and group 3 included 16 patients with stage Ic secondary to intraoperative rupture.
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Conclusion & Impact:RESULTS: Overall survivals were not different among the three groups (P>0.05).
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Cerrahi işlemler · operatif · Yumurtalık neoplazmları

Abstract

OBJECTİVE: To investigate of prognostic importance of intraoperative cyst rupture in patients with early stage epithelial ovarian carcinoma MATERIAL AND METHODS: The prognostic influence of intraoperative tumor rupture was examined in 49 patients with stage I malignant ovarian carcinoma were treated between 1990 and 1998. The patients were divided into three groups. Group 1 included 14 patients with stage Ia, group 2 included 19 patients with stage Ic and group 3 included 16 patients with stage Ic secondary to intraoperative rupture. Survival analysis was performed by using the Kaplan-Maier technique. Multivariate analysis was made by using the Cox's proportional hazard model. RESULTS: Overall survivals were not different among the three groups (P>0.05). The multivariate analysis identified that degree of differentiation as only prognostic indicator (P=0.07, hazard ratio=3.1). CONCLUSION: In conclusion, our study shows that rupture of the tumor during surgery has no influence on survival rates, however, grade is an important prognostic factor in stage I epithelial ovarian carcinoma.

Özet

AMAÇ: Erken evre epitelyal over karsinomlarında operasyon anında meydana gelen tümör rüptürlerinin prognostik önemini araştırmak MATERYAL ve METOD: 1990-98 tarihleri arasında cerrahi tedavi uygulanan 49 evre I epitelyal over karsinomu olgusunun verileri incelendi. Olgular üç gruba ayrılarak birinci gruba evre Ia hastalığı olan 14 olgu, ikinci gruba evre Ic hastalığı olan 19 olgu ve üçüncü gruba ise intraoperatif kist rüptürü olan 16 olgu dahil edildi. Sağ kalım analizi için Kaplan-Maier tekniği, multivariate analiz için Cox's proportional hazard model kullanıldı. BULGULAR: Sağ kalım analizinde gruplar arasında anlamlı farklılık bulunmadı (P>0.05). Multivariate analizde prognozu etkileyen tek faktör grade olarak bulundu(P=0.07, kümülatif risk=3.1). SONUÇLAR: Sonuç olarak bu çalışma intraoperatif tümör rüptürünün prognozu olumsuz etkilemediğini bununla beraber gradein önemli bir prognostik faktör olduğunu göstermiştir.

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Cite This Article

SAYGILI, U., GÜÇLÜ, S., POSACI, C., KOYUNCUOĞLU, M., USLU, T., ERTEN, O. (2002). Prognostik importance of intraoperative cyst rupture in early stage epithelial ovarian carcinoma. Medical Network Klinik Bilimler ve Doktor, Cilt: 8 - Sayı: 2, 248–251. https://ajindex.com/articles/278622

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