Journals / Journal of Neurological Sciences (Turkish) / 2010 / Cilt: 27 - Sayı: 4

Sıçanlarda spasyal belleğin adölesan dönem süresince gelişimi

Development of spatial memory during adolescent period in rats

Pages
407–413
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

On the probe trial, 21 days old rats spent less time in the target quadrant and spent more time in the opposite quadrant (p

📌 3 Key Takeaways

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Objective & Hypothesis:It is well known that, hippocampus is center of the spatial learning and memory.
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Key Findings & Data:The aim of this study is to evaluate hippocampal functional and cellular differentiation during the adolescent period of rats.Wistar Albino male and female rats at 21, 38, 60 days of age were used.
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Conclusion & Impact:On the probe trial, 21 days old rats spent less time in the target quadrant and spent more time in the opposite quadrant (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

It is well known that, hippocampus is center of the spatial learning and memory. Hippocampus changed during the adolescent periyod that is brain development continued. The aim of this study is to evaluate hippocampal functional and cellular differentiation during the adolescent period of rats.Wistar Albino male and female rats at 21, 38, 60 days of age were used. Spatial learning and memory was evaluated using by Morris water maze. During learning period, escape latencies decrease significantly over days in all groups. On the 3rd and 4th day, 21 days old rats spent longer time to reach the platform than the other groups. (F(1,34) = 90.657, p < 0.001). On the probe trial, 21 days old rats spent less time in the target quadrant and spent more time in the opposite quadrant (p

Özet

Bilindiği gibi hipokampus spasyal öğrenme ve belleğin merkezidir. Beyin gelişiminin devam ettiği adölesan dönem boyunca hipokampus da değişim geçirir. Bu çalışmanın amacı sıçanlarda adölesan dönem boyunca hipokampusun hücresel ve fonksiyonel değişimini araştırmaktır.Çalışmada 21, 38 ve 60 günlük dişi ve erkek sıçanlar kullanılmıştır. Spasyal öğrenme ve bellek Morris su tankı ile değerlendirilmiştir. 4 günlük öğrenme sürecinde tüm gruplarda platforma ulaşma süreleri giderek kısalmıştır. 3 ve 4. günde 21 günlük sıçanların platformu bulma süresinin diğer gruplara göre daha uzun olduğu görülmüştür (sırasıyla; p < 0.05, p

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Cite This Article

ÖZBAL, S., TUGYAN, K., ÇETİN, F., AKSU, İ., YALAZ, G., ARDA, S. G., UYSAL, N., DAYI, A. (2022). Sıçanlarda spasyal belleğin adölesan dönem süresince gelişimi. Journal of Neurological Sciences (Turkish), Cilt: 27 - Sayı: 4, 407–413. https://ajindex.com/articles/565408

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