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Journals / Journal of Istanbul University Faculty of Dentistry / 2017 / Cilt: 51 - Sayı: 3

Cerrahi Destekli Hızlı Üst Çene Genişletmesi Sırasında Damar İçi Traneksamik Asit Kullanımı Kan Kaybını Azaltır mı?

DOES INTRAVENOUS TRANEXAMIC ACID REDUCE BLOOD LOSS DURING SURGICALLY ASSISTED RAPID PALATAL EXPANSION?

Erol CANSIZ
Zerrin ÇEBİ
Emine AKBAŞ
Sabri Cemil İŞLER
Sırmahan ÇAKARER
Pages
32–37
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Blood loss during SARPE was statistically significantly less in the study group than the control group (p=0.0001).Conclusion: Preoperative IV administration of TXA can effectively control blood loss during when SARPE with pterygoid disjunction is performed

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: The purpose of this study was to evaluate the efficacy of tranexamic acid (TXA) in reducing blood loss during surgically assisted rapid palatal expansion (SARPE) procedure.Subjects and Methods: A total of 34 patients (12 male, 22 female) who had been treated surgically under general anesthesia with SARPE including pterygoid disjunction for transverse maxillary deficiency (TMD) were included in this study.
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Key Findings & Data:The study group (n=17) received intravenous (IV) TXA 10 mg/kg as a preoperative bolus; the control group (n=17) received normal saline solution.
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Conclusion & Impact:Results: Blood loss during SARPE was statistically significantly less in the study group than the control group (p=0.0001).Conclusion: Preoperative IV administration of TXA can effectively control blood loss during when SARPE with pterygoid disjunction is performed
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: The purpose of this study was to evaluate the efficacy of tranexamic acid (TXA) in reducing blood loss during surgically assisted rapid palatal expansion (SARPE) procedure.Subjects and Methods: A total of 34 patients (12 male, 22 female) who had been treated surgically under general anesthesia with SARPE including pterygoid disjunction for transverse maxillary deficiency (TMD) were included in this study. The study group (n=17) received intravenous (IV) TXA 10 mg/kg as a preoperative bolus; the control group (n=17) received normal saline solution. Preoperative and postoperative haemoglobin and haematocrit values, intraoperative blood loss, and any blood product transfusion were recorded. Results: Blood loss during SARPE was statistically significantly less in the study group than the control group (p=0.0001).Conclusion: Preoperative IV administration of TXA can effectively control blood loss during when SARPE with pterygoid disjunction is performed

Özet

Amaç: Bu çalışmada damar içi traneksamik asit (TXA) kullanımının cerrahi destekli hızlı üst çene genişletmesi sırasında (SARPE) sırasında meydana gelen kan kaybı üzerine etkisinin değerlendirilmesi amaçlanmıştır.Hastalar ve Yöntem: Bu çalışmaya üst çenede transvers yetersizliği (ÜTY) bulunan ve genel anestezi altında pterigoid ayırma yapılarak SARPE ile tedavi edilen toplamda 34 hasta (12 erkek, 22 kadın) dahil edilmiştir. Çalışma grubuna (n=17) damar içi 10 mg/kg TXA girişim öncesinde; kontrol grubuna ise (n=17) yine damar içine serum fizyolojik verilmiştir. Girişim öncesinde ve sonrasında hemoglobin ve hematokrit değerleri, girişim sırasındaki kan kaybı ve kan ürünleri transfüzyonu kaydedilmiştir.Bulgular: SARPE girişimi sırasında çalışma grubunda ölçülen kan kaybı değerlerinin kontrol grubuna göre daha düşük olduğu ve bu farkın istatistiksel olarak çok ileri düzeyde anlamlı olduğu belirlenmiştir (p=0.0001).Sonuç: Girişim öncesinde damar içi yolla TXA uygulaması ile pterigoid ayırma yapılan SARPE işlemi sırasında meydana gelen kan kaybı etkili bir şekilde kontrol altına alınabilir

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Cite This Article

CANSIZ, E., ÇEBİ, Z., AKBAŞ, E., İŞLER, S. C., ÇAKARER, S. (2022). Cerrahi Destekli Hızlı Üst Çene Genişletmesi Sırasında Damar İçi Traneksamik Asit Kullanımı Kan Kaybını Azaltır mı?. Journal of Istanbul University Faculty of Dentistry, Cilt: 51 - Sayı: 3, 32–37. https://ajindex.com/articles/563766

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