Journals / Journal of Clinical and Analytical Medicine / 2015 / Cilt: 6 - Sayı: 2

Kromofob Renal Hücreli Kanser: Radikal Nefrektomi Serisinde Saptanan 21 Vakanın Değerlendirilmesi

Chromophobe Renal Cell Carcinoma: Evaluation of 21 Cases with a Large Radical Nephrectomy Series

Pages
177–179
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Discussion: Despite the pressing need for more studies to determine diagnosticand prognostic tools, chromophobe renal cell carcinoma of kidney have goodprognostic features.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Chromophobe renal cell carcinoma comprises % 4-10 of the total casesof RCC.
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Key Findings & Data:Material and Method: Between January 2001 and April 2013, 352patients with regular follow-up and the diagnosis of localized or metastaticRCC treated with surgery were included in this study.
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Conclusion & Impact:Discussion: Despite the pressing need for more studies to determine diagnosticand prognostic tools, chromophobe renal cell carcinoma of kidney have goodprognostic features.
🔬Design:Research Article
📍Scope:2001 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Chromophobe renal cell carcinoma comprises % 4-10 of the total casesof RCC. In this study we aim to determine frequency, clinical outcome andsurvival of chromophobe renal cell carcinoma in a large radical nephrectomyseries. Material and Method: Between January 2001 and April 2013, 352patients with regular follow-up and the diagnosis of localized or metastaticRCC treated with surgery were included in this study. Evaluated in the context of the records of these patients were analyzed in chromophobe RCC.Mean follow-up time was 37.12 months. Results: 21 of 352 RCC patientswere diagnosed as chromophobe RCC. All of the patients ranged from pathologic stage pT1-2. None of the pathology was observed multifocality andmicrovascular invasion.There was no lymph node or distant metastasis withlong term follow-up and 5-year disease-specific survival was 100%. Discussion: Despite the pressing need for more studies to determine diagnosticand prognostic tools, chromophobe renal cell carcinoma of kidney have goodprognostic features.

Özet

Amaç: Kromofob renal hücreli kanser (kRHK) bütün RHK`lerin %4-10`unuoluşturmaktadır. Bu hastaların uzun süreli takiplerine ilişkin elimizde kısıtlı sayıda bilgi bulunmaktadır. Bu çalışmanın amacı kRHK sıklığını, klinik seyrini ve sağkalımını geniş RHK hasta serisinde değerlendirmektir. Gereç ve Yöntem: Ocak 2001 ve Nisan 2013 tarihleri arasında lokalize veya metastatikRHK ön tanısı ile cerrahi uygulanmış, düzenli takipleri olan 352 hasta bu çalışmanın kapsamına alınmıştır. Bu hastaların kayıtları kromofob RHK bağlamında değerlendirilip analiz edilmiştir. Ortalama takip süresi 37,12 ay olarakbelirlenmiştir. Bulgular: 352 hastanın 21`ine kromofob RHK tanısı konulmuştur. kRHK hastaların tümünde patolojik evre pT1-2 aralığındaydı. Hastalarınhiçbirinde multifokalite ve mikrovasküler invazyon görülmedi. Hiçbir hastadatanı anında ya da uzun süreli takiplerde lenf nodu veya uzak metastaz saptanmadı. 5 yıllık hastalığa spesifik sağkalım %100 olarak saptandı. Tartışma:kRHK; klinik seyri, sağkalımı ve prognostik araçların tam olarak belirlenmesi için daha çok çalışmaya ihtiyaç duyulsa da kromofob RHK çok iyi prognostik özellikler göstermektedir.

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Cite This Article

SARICI, H., TELLİ, O., YÜCETÜRK, C. N., ÖZGÜR, B. C., KABAR, M. (2022). Kromofob Renal Hücreli Kanser: Radikal Nefrektomi Serisinde Saptanan 21 Vakanın Değerlendirilmesi. Journal of Clinical and Analytical Medicine, Cilt: 6 - Sayı: 2, 177–179. https://ajindex.com/articles/561399

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