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Journals / Joint diseases and related surgery / 2021 / Cilt: 32 - Sayı: 3

The effect of the platelet-rich plasma on osteogenicpotential of the periosteum in an animal bone defect model

Meriç ÇIRPAR
İbrahim Deniz CANBEYLİ
Birhan OKTAŞ
Önder BOZDOĞAN
Elif ŞANLI
Pages
668–675
Publication Date
2022-10-19
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Results: In the PRP applied group, healing of the bone defectat four weeks was significantly better than the other groups interms of histological new bone formation (p

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Objective & Hypothesis:Objectives: This study aims to investigate whether plasma-richplasma (PRP) enhances the osteogenic potential of periostealgrafts used to repair bone defects and maintains both histologicallyand biomechanically more durable bone tissue.
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Key Findings & Data:Materials and methods: A standard bone defect was formed tothe left femurs of 54 Sprague-Dawley rats and three groups wereformed.
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Conclusion & Impact:Results: In the PRP applied group, healing of the bone defectat four weeks was significantly better than the other groups interms of histological new bone formation (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: This study aims to investigate whether plasma-richplasma (PRP) enhances the osteogenic potential of periostealgrafts used to repair bone defects and maintains both histologicallyand biomechanically more durable bone tissue. Materials and methods: A standard bone defect was formed tothe left femurs of 54 Sprague-Dawley rats and three groups wereformed. In the first group (n=18), no periosteal repair was donefor bone defect. In the second group (n=18), periosteal graft tissuewas sutured to cover the defect entirely. In the third group (n=18),before periosteal repair, a 1 mL of PRP fibrin was applied into thebone defect. All femoral specimens were compared histologicallyat four and six weeks and biomechanically by three-pointbending test at six weeks after treatment. Results: In the PRP applied group, healing of the bone defectat four weeks was significantly better than the other groups interms of histological new bone formation (p

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Cite This Article

ÇIRPAR, M., CANBEYLİ, İ. D., OKTAŞ, B., BOZDOĞAN, Ö., ŞANLI, E. (2022). The effect of the platelet-rich plasma on osteogenicpotential of the periosteum in an animal bone defect model. Joint diseases and related surgery, Cilt: 32 - Sayı: 3, 668–675. https://ajindex.com/articles/559225

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