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Dergiler / Joint diseases and related surgery / 2021 / Cilt: 32 - Sayı: 3

The effect of the platelet-rich plasma on osteogenicpotential of the periosteum in an animal bone defect model

Meriç ÇIRPAR
İbrahim Deniz CANBEYLİ
Birhan OKTAŞ
Önder BOZDOĞAN
Elif ŞANLI
Sayfa
668–675
Yayın Tarihi
2022-10-19
DOI
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Results: In the PRP applied group, healing of the bone defectat four weeks was significantly better than the other groups interms of histological new bone formation (p

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Amaç & Hipotez:Objectives: This study aims to investigate whether plasma-richplasma (PRP) enhances the osteogenic potential of periostealgrafts used to repair bone defects and maintains both histologicallyand biomechanically more durable bone tissue.
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Temel Bulgular & Veri:Materials and methods: A standard bone defect was formed tothe left femurs of 54 Sprague-Dawley rats and three groups wereformed.
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Sonuç & Katkı:Results: In the PRP applied group, healing of the bone defectat four weeks was significantly better than the other groups interms of histological new bone formation (p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objectives: This study aims to investigate whether plasma-richplasma (PRP) enhances the osteogenic potential of periostealgrafts used to repair bone defects and maintains both histologicallyand biomechanically more durable bone tissue. Materials and methods: A standard bone defect was formed tothe left femurs of 54 Sprague-Dawley rats and three groups wereformed. In the first group (n=18), no periosteal repair was donefor bone defect. In the second group (n=18), periosteal graft tissuewas sutured to cover the defect entirely. In the third group (n=18),before periosteal repair, a 1 mL of PRP fibrin was applied into thebone defect. All femoral specimens were compared histologicallyat four and six weeks and biomechanically by three-pointbending test at six weeks after treatment. Results: In the PRP applied group, healing of the bone defectat four weeks was significantly better than the other groups interms of histological new bone formation (p

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Bu Makaleye Atıf Yap

ÇIRPAR, M., CANBEYLİ, İ. D., OKTAŞ, B., BOZDOĞAN, Ö., ŞANLI, E. (2022). The effect of the platelet-rich plasma on osteogenicpotential of the periosteum in an animal bone defect model. Joint diseases and related surgery, Cilt: 32 - Sayı: 3, 668–675. https://ajindex.com/articles/559225

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Kaynakça (13)

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