Journals / Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi / 2016 / Cilt: 0 - Sayı: ÖZEL SAYI SUPPLEMENT

Low-Grade Endometrial Stromal Sarcoma Following Tamoxifen Treatment

Tamoksifen Tedavisini Takiben Gelişen Düşük Gradeli Endometriyal Stromal Sarkom

Pages
9–10
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Up to now, nearly 65 endometrial stromal sarcoma cases have been reported after TMX treatment in the literature, and a meticulous follow-up is important in patients that will receive TMX therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Tamoxifen TMX is supposed to be related with development of uterine sarcomas.
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Key Findings & Data:These sarcomas mostly appear 5 or 8 years after TMX administration and tend to display an aggressive behaviour.
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Conclusion & Impact:Up to now, nearly 65 endometrial stromal sarcoma cases have been reported after TMX treatment in the literature, and a meticulous follow-up is important in patients that will receive TMX therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Endometriyal stromal sarkom · tamoksifen · meme

Abstract

Tamoxifen TMX is supposed to be related with development of uterine sarcomas. Due to the low incidence of uterine sarcomas, establishment of a causal relationship with TMX is difficult. These sarcomas mostly appear 5 or 8 years after TMX administration and tend to display an aggressive behaviour. In this report, we present a rare case of endometrial stromal sarcoma detected in a breast cancer patient who had been treated with TMX for only two years. Up to now, nearly 65 endometrial stromal sarcoma cases have been reported after TMX treatment in the literature, and a meticulous follow-up is important in patients that will receive TMX therapy.

Özet

Tamoksifen TMX kullanımının, uterin sarkom gelişimi ile ilişkili olduğu düşünülmektedir. Uterin sarkomların görülme insidansının düşük olması nedeniyle TMX kullanımına bağlı nedensel bir ilişki kurmak zordur. Bu sarkomlar çoğunlukla TMX tedavisi başladıktan 5 ile 8 yıl sonrasında ortaya çıkarlar ve daha agresif bir davranış sergileme eğilimindedirler. Bu yazıda, sadece iki yıl TMX tedavisi almış meme kanseri olan hastada tespit edilen endometriyal stromal sarkom olgusunu sunduk. Literatürde şimdiye kadar yaklaşık 65 TMX kullanımı sonrası gelişen uterin sarkom vakası rapor edilmiştir. TMX tedavisi alan meme kanseri hastalarında jinekolojik titiz takip esastır.

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Cite This Article

BEDİR, R., URAL, Ü. M. (2022). Low-Grade Endometrial Stromal Sarcoma Following Tamoxifen Treatment. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi, Cilt: 0 - Sayı: ÖZEL SAYI SUPPLEMENT, 9–10. https://ajindex.com/articles/558768

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References (4)

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