Journals / Respiratory Case Reports / 2018 / Cilt: 7 - Sayı: 2

A Rare Cause of Massive Pulmonary Hemorrhage: Invasive Actinomycosis

Masif Pulmoner Hemorajinin Nadir bir Nedeni: İnvaziv Aktinomikoz

Pages
86–89
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Pulmonary angioinvasive infections like actinomycosis must be kept in mind in the absence of bronchialcarcinoma or other frequently encountered diseases in casesof massive pulmonary hemorrhage.

📌 3 Key Takeaways

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Objective & Hypothesis:Pulmonary actinomycosis is a severe clinical condition that may cause death if unrecognized.
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Key Findings & Data:A 52-year-old formerlyimmunocompetent man was admitted to the hospitaldue to blood-streaked sputum.
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Conclusion & Impact:Pulmonary angioinvasive infections like actinomycosis must be kept in mind in the absence of bronchialcarcinoma or other frequently encountered diseases in casesof massive pulmonary hemorrhage.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Pulmonary actinomycosis is a severe clinical condition that may cause death if unrecognized. It mayoccur in patients who were previously healthy or maydevelop in patients with chronic immunosuppressantconditions. Presently described is a rare case of massive pulmonary hemorrhage with a related angioinvasive Actinomyces infection. A 52-year-old formerlyimmunocompetent man was admitted to the hospitaldue to blood-streaked sputum. A computed tomography image of the thorax taken after the patient’sclinical status suddenly worsened revealed total collapse of the left lung. No tumoral lesion was observed, but extensive necrosis of the mucosa of bothmain bronchi with massive hemorrhage in the leftmain bronchus was noticed in an urgent bronchoscopy performed in the intensive care unit. A histopathological examination of the mucosal punch biopsy demonstrated aggregates of filamentous Grampositive organisms indicating Actinomyces infection. Selective embolization of a branch of the feeding artery wassuccessful to control the hemorrhage, but necrotizing pneumonia emerged and the patient could not be dischargedfrom the intensive care unit. He was later lost despite 40days of treatment with intravenous penicillin-G plus antifungal therapy. Pulmonary angioinvasive infections like actinomycosis must be kept in mind in the absence of bronchialcarcinoma or other frequently encountered diseases in casesof massive pulmonary hemorrhage.

Özet

Pulmoner aktinomikoz geç tanı konulduğunda ölümle sonuçlanabilecek bir durumdur. Daha çok immün yetmezliği olan bireylerde beklendiği gibi immünkompetan kişilerde de görülebileceği unutulmamalı- dır. Bu yazıda invaziv pulmoner aktinomikoza bağlı masif pulmoner hemoraji gelişen nadir bir olgu sunulmuştur. Elli iki yaşında bilinen immünsupresif durumu olmayan erkek hasta ağızdan balgamla karışık kan gelmesi nedeni ile yatırıldı. Elektif bronkoskopi planlanan hastanın genel durumunda ani kötüleşme nedeni ile çekilen toraks bilgisayarlı tomografisinde sol akciğerde başvuruda olmayan total atelektazi saptandı. Yoğun bakım ünitesinde yapılan acil bronkoskopide sol ana broşta masif hemoraji ve her iki ana bronş mukozasında yaygın nekrotik görünüm izlendi. Alınan mukozal biyopsinin patolojik incelemesinde aktinomikozla uyumlu gram pozitif filamentöz bakteri agregatları izlendi. Bronşiyal arter kateterizasyonunda ekstravazasyon saptanan artere embolizasyon işlemi uygulandı. Ancak yerine gelişen bilateral nekrotizan pnömoni nedeni ile hastanın yoğun bakım takibine devam edildi. Hasta IV penisilin G ve anti fungal tedaviye rağmen 40 günlük takip sonrasında kaybedildi. Masif pulmoner hemoraji olgularında sıklıkla kanama yapan hastalıklar ve tümoral lezyonların yokluğunda ayırıcı tanıda aktinomikoz gibi anjioinvaziv enfeksiyonlar düşünülmelidir.

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Cite This Article

İNECİKLİ, M. F., KOSTAKOĞLU, U., BEDİR, R., BATÇIK, Ş., ŞAHİN, Ü., SEVİLGEN, G., ÖZYURT, S., KARA, B. Y., MEMOĞLU, M. (2022). A Rare Cause of Massive Pulmonary Hemorrhage: Invasive Actinomycosis. Respiratory Case Reports, Cilt: 7 - Sayı: 2, 86–89. https://ajindex.com/articles/588990

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