Journals / İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası / 2002 / Cilt: 65 - Sayı: 4

A new method in trachead reconnstructiion: The application of cyanoacrylate-covered tracheal

Trakea rekonstrüksiyonunda yeni bir yöntem: Sıçanlarda cynanoacrylate kaplanmış trakea allogrefti uygulaması

Pages
255–262
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our study suggested that cyanoacrylate was successful in preser-vation of trachéal allografts and prevented the rejection of the graft through a barrier mechanism.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A new method in trachéal reconstruction: The application of cyanoacrylate-covered trachéal allograft in rats.
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Key Findings & Data:Tracheas of the first rats of each group were removed and then separated into pieces.
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Conclusion & Impact:Our study suggested that cyanoacrylate was successful in preser-vation of trachéal allografts and prevented the rejection of the graft through a barrier mechanism.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A new method in trachéal reconstruction: The application of cyanoacrylate-covered trachéal allograft in rats. In this experimental study, it was aimed to investigate the efficacy of tissue adhesive cyanoacrylate in the protection of trachéal allografts. Fortytwo Wistar Albino rats were divided into two groups. Tracheas of the first rats of each group were removed and then separated into pieces. While trachéal pieces were covered with cyanoacrylate in the first group, no preservation was not applied to the second group. Trachéal grafts were placed into the external fascia of musculus rectalis of other rats. On the 23rd day, allografts were examined by histopathologic techniques. Our study suggested that cyanoacrylate was successful in preser-vation of trachéal allografts and prevented the rejection of the graft through a barrier mechanism.

Özet

Bu deneysel çalışmada doku yapıştırıcısı cyanoacrylate'nin trakeal allogreftlerin korunmasında kullanılabilirliğinin araştırılması amaçlandı. Çalışma sırasında toplam 42 adet Wistar Albino sıçan iki gruba ayrıldı. Her iki grubun birinci deneklerinin trakeaları çıkartılıp, parçalara ayrıldı. Trakea parçalan ilk grupta doku yapıştırıcısı cyanoacrylate ile korunurken, ikinci denek grubunda korunma uygulanmadı. Trakeal greftler diğer deneklerin rektus adale dış fasyasında hazırlanan ceplere yerleştirildi ve allogreftler 23. günde histopatolojik yöntemlerle incelendi. Çalışmamızda cyanoacrylate'ın trakeal allogreftlerin korunmasında başarılı olduğu ve greftin reddedilmesini barier etkisiyle önlediği düşünülmüştür.

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Cite This Article

ÖZTÜRK, Ö. Y., IŞITMANGİL, T., ÇERMİK, H., ERDİK, O., TOKER, A. (2022). A new method in trachead reconnstructiion: The application of cyanoacrylate-covered tracheal. İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası, Cilt: 65 - Sayı: 4, 255–262. https://ajindex.com/articles/553728

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