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Journals / İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası / 2003 / Cilt: 66 - Sayı: 2

Microalbuminuria and QT dispersion in patients with newly diagnosed systemic hypertension

Yeni tanı konmuş sistemik hipertansiyonlu hastalarda mikroalbüminüri ve QT dispersiyonu

Kerem SEZER
Ramazan GEN
Ahmet ÇAMSARI
Aziz YAZAR
Oğuz ULU
Alper Ahmet KIYKIM
Pages
96–100
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Corrected QT (QTc) dispersion in MA+ (62.1±23.9 ms) and in MA- (55.8+19 m) groups was significantly higher than controls (29.2±10.6 ms) (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Microalbuminuria and QT dispersion in patients with newly diagnosed systemic hypertension.
📊
Key Findings & Data:It has been shown to be increased QT dispersion in hypertension.
💡
Conclusion & Impact:Corrected QT (QTc) dispersion in MA+ (62.1±23.9 ms) and in MA- (55.8+19 m) groups was significantly higher than controls (29.2±10.6 ms) (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Microalbuminuria and QT dispersion in patients with newly diagnosed systemic hypertension. Microalbuminuria (MA) and left ventricular hypertrophy (LVH) are associated with incre-ased cardiovascular morbidity and mortality in hypertensive patients. It has been shown to be increased QT dispersion in hypertension. The aim of our study was to examine if there was any association between MA and QT dispersion in hypertensive patients. Eighty-one consecu-tive newly diagnosed hypertensive patients and 33 healthy controls (15 female, 18 male, mean age: 46.2±11.1 yr) were enrolled in the study. Patients with hypertension were divided into two groups: nine-teen patients in MA positive (MA+) group (8 female and 11 male, mean age: 51.9±9.3 yr) and 62 patients in MA negative (MA-) group (29 female and 33 male, mean age: 50.2+9.8 yr). Echocardiography, 12-lead electrocardiography, three times albumin analysis in 24-hours urine and rutin biochemical tests were performed to all the patients. Corrected QT (QTc) dispersion in MA+ (62.1±23.9 ms) and in MA- (55.8+19 m) groups was significantly higher than controls (29.2±10.6 ms) (p

Özet

Hipertansif hastalarda mikroalbüminüri (MA), sol ventrikül hipertrofisi (S VH), artmış kardiyovasküler morbidite ve mortalite ile ilişkilidir. Hipertansiyonda QT dispersiyonunun normal populasyona göre daha yüksek oranda olduğu gösterilmiştir. Bu çalışmanın amacı hipertansif hastalarda MA ile QT dispersiyonu arasında bir ilişkinin olup olmadığını araştırmaktır. Çalışmaya daha önce tedavi almamış yeni tanı konmuş ardısıra gelen 81 hipertansif hasta ve 33 (15 kadın, 18 erkek, ortalama yaş: 46.2±11.1 yıl) sağlıklı kontrol alındı. Hipertansif hastalar 19 MA pozitif (MA+) (8 kadın, 11 erkek, ortalama yaş: 51.5±9.3 yıl) ve 62 MA negatif (MA-) (29 kadın, 33 erkek, ortalama yaş: 50.2±9.8 yıl) olmak üzere iki gruba ayrıldı. Tüm hastalara 12 derivasyonlu elektrokardiyografi, ekokardiyografi, üç kez 24 saatlik idrarda MA tayini ve rutin biyokimyasal testler yapıldı. MA+ ve MA- gruplarda düzeltilmiş QT (dQT) dispersiyonu (sırasıyla 62.1±23.9 ms ve 55.8±19 ms) kontrollere (29.2±10.6 ms) göre anlamlı olarak daha yüksek bulundu (p

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Cite This Article

SEZER, K., GEN, R., ÇAMSARI, A., YAZAR, A., ULU, O., KIYKIM, A. A. (2022). Microalbuminuria and QT dispersion in patients with newly diagnosed systemic hypertension. İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası, Cilt: 66 - Sayı: 2, 96–100. https://ajindex.com/articles/553703

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