Journals / İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi / 1999 / Cilt: 6 - Sayı: 2

Fibrinogen and coronary artery disease

Fibrinojen ve koroner arter hastalığı

Pages
136–139
Publication Date
2022-10-17
DOI
—
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Additionally single vessel patients had 165 and double vessel patients had 135 and triple vessel patients had 60, The levels of plasma fibrinogen in the patients with total luminal occlusion were significantly higher than the patients without total luminal occlusion (4.76±1.36 g/l vs 4.21±1.04g/l, p

📌 3 Key Takeaways

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Objective & Hypothesis:It has previously been shown that fibrinogen is involved in the pathogenesis of atherosclerosis and coronary artery disease.
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Key Findings & Data:The study population included 360 patients with coronary artery disease, 129 patients had total luminal occlusion.
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Conclusion & Impact:Additionally single vessel patients had 165 and double vessel patients had 135 and triple vessel patients had 60, The levels of plasma fibrinogen in the patients with total luminal occlusion were significantly higher than the patients without total luminal occlusion (4.76±1.36 g/l vs 4.21±1.04g/l, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective. It has previously been shown that fibrinogen is involved in the pathogenesis of atherosclerosis and coronary artery disease. However, only a few studies have shown the correlation between the fibrinogen level and the extent of coronary artery disease and the presence of total luminal occlusion. The purpose of this study was to verify the existence of a correlation between fibrinogen and the presence of total luminal occlusion and the extent of coronary artery disease in our study population. Methods and Results. The patients were characterized with regard to presence or absence of total luminal occlusion and the extent of coronary artery disease (single, double and triple vessels). The study population included 360 patients with coronary artery disease, 129 patients had total luminal occlusion. The remaining patients did not have total luminal occlusion. Additionally single vessel patients had 165 and double vessel patients had 135 and triple vessel patients had 60, The levels of plasma fibrinogen in the patients with total luminal occlusion were significantly higher than the patients without total luminal occlusion (4.76±1.36 g/l vs 4.21±1.04g/l, p

Özet

Amaç. Fibrinojenin aterosklerozis ve koroner arter hastalığının patogenezinde yer aldığı daha önceden gösterilmiştir. Fakat fibrinojen düzeyinin koroner arter hastalığının yaygınlığı ve tam tıkanıklığın varlığı ile ilişkisi sadece birkaç çalışmada gösterilmiştir. Bu çalışmanın amacı çalışma populasyonumuzda koroner arter hastalığının yaygınlığı ve tam tıkanıklığın varlığı ile fibrinojen arasında bir ilişkinin varlığını belirlemek idi. Metod ve Bulgular. Hastalar tam tıkanıklığın varlığına veya yokluğuna ve koroner arter hastalığının yaygınlığına (tek damar, iki damar ve üç damar) göre sınıflandırıldı. Çalışma grubu koroner arter hastalığı olan 360 hastayı içeriyordu. Bu hastaların 129'unda tam tıkanıklık varken geri kalan hastalarda tam tıkanıklık yoktu. Ayrıca tek damar hastalığı 165, iki damar hastalığı 135, üç damar hastalığı 60 hastada mevcuttu. Tam tıkanıklığı olan hastaların plazma fibrinojen düzeyleri tam tıkanıklığı olmayan hastalardan daha yüksekti (4.76±1.36 g/l'e karşın 4.21±1.04 g/l, p

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Cite This Article

KOŞAR, F., HİSAR, İ., AYTAN, Y., VAROL, E., TANDOĞAN, İ. (2022). Fibrinogen and coronary artery disease. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, Cilt: 6 - Sayı: 2, 136–139. https://ajindex.com/articles/549661

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