AI Summary & Key Takeaways
AI InsightThis case was presented to highlight that cytomegalovirus must be taken into consideration in etiology of hepatitis.
📌 3 Key Takeaways
Abstract
Cytomegalovirus infection is commonly seen infection in the world, and rate of adults experiencing this infection reaches up to 90% indeveloping countries. The infection limits itself in healthy population, being symptomatic in 10% of them. Although symptomatic casesusually present as mononucleosis--like syndrome, they rarely cause organ specific complications. In this article, we present case of acute,severe Cytomegalovirus infection manifesting as persistent high fever, elevations of aspartate aminotransferase and alaninaminotransferase, high INR, thrombocytopenia, hepatomegaly, and splenomegaly in 40 year old immunocompetent adult. The patient wasdiagnosed as cytomegalovirus hepatitis and given gancyclovir 2x250 mg IV for 14 days. He was discharged upon the improvement of hisgeneral status, development of seroconversion and decline of liver enzymes. This case was presented to highlight that cytomegalovirus must be taken into consideration in etiology of hepatitis.
Özet
Sitomegalovirus enfeksiyonu tüm dünyada sık görülen bir viral enfeksiyon olup, gelişmekte olan ülkelerde erişkinlerin enfeksiyonu geçirmeoranı %90'lara çıkmaktadır. Sağlıklı erişkinde kendini sınırlayan enfeksiyon %10 oranında semptomatiktir. Semptomatik seyirli olgular sıklıklamononükleoz benzeri sendrom şeklinde kendini göstermesine rağmen nadiren organ spesifik komplikasyonlara neden olurlar. Bu olgusunumunda, persistan ateş, aspartat aminotransferaz, alanin aminotransferaz ve INR yüksekliği, trombositopeni karaciğer ve dalakbüyüklüğü ile seyreden akut ciddi seyirli, 40 yaşında immün sistemi sağlam erişkin Sitomegalovirus olgusu sunulmuştur. Sitomegalovirushepatiti tanısı ile i.v. 2>