In this paper, several different purification and characterization methods of multi functional enzyme paraoxonase 1 EC 3.3.8.1 was reviewed.
📌 3 Key Takeaways
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Objective & Hypothesis:Human serum paraoxonase1 hPON1 is a calcium dependent enzyme, which has an important physiological role in organism with detoxification, antioxidant and also antiatherogenic properties.
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Key Findings & Data:PON1 is mostly synthesized from the liver than secreted in serum with located on HDL.
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Conclusion & Impact:In this paper, several different purification and characterization methods of multi functional enzyme paraoxonase 1 EC 3.3.8.1 was reviewed.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Paraoxonase1 · Chromatography Methods · Enzyme Purification and Characterization
Abstract
Human serum paraoxonase1 hPON1 is a calcium dependent enzyme, which has an important physiological role in organism with detoxification, antioxidant and also antiatherogenic properties. PON1 is mostly synthesized from the liver than secreted in serum with located on HDL. In order to better understand the molecular mechanism of paraoxonase 1, researchers have been increasingly interested in the development of various methods for obtaining the enzyme in pure form over the last decades. In this paper, several different purification and characterization methods of multi functional enzyme paraoxonase 1 EC 3.3.8.1 was reviewed.
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