The thermal stability of the co-crystalswas investigated by using DSC and it was determinated that the melting points of the cocrystals1 and 2 were lower and in-between from those of their coformers, respectively.
📌 3 Key Takeaways
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Objective & Hypothesis:Two co-crystals of p-aminobenzoic acid with isonicotinamide and pyrazine were preparedin acetone-ethanol solution by solvent evaporation method in the 1:1 cytochiometric ratio.Their structures were characterized by FT-IR, 1H NMR and 13C NMR spectroscopies,powder X-Ray diffraction and differential scanning calorimetry (DSC) method.
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Key Findings & Data:Both of thestructures have shown the COOH/N heterosynthon.
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Conclusion & Impact:The thermal stability of the co-crystalswas investigated by using DSC and it was determinated that the melting points of the cocrystals1 and 2 were lower and in-between from those of their coformers, respectively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Two co-crystals of p-aminobenzoic acid with isonicotinamide and pyrazine were preparedin acetone-ethanol solution by solvent evaporation method in the 1:1 cytochiometric ratio.Their structures were characterized by FT-IR, 1H NMR and 13C NMR spectroscopies,powder X-Ray diffraction and differential scanning calorimetry (DSC) method. Both of thestructures have shown the COOH/N heterosynthon. The thermal stability of the co-crystalswas investigated by using DSC and it was determinated that the melting points of the cocrystals1 and 2 were lower and in-between from those of their coformers, respectively.
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Cite This Article
ÖZBEK, F. E. (2022). Synthesis and Characterization of Two New Co-Crystals: p-Aminobenzoic Acid with Isonicotinamide and Pyrazine (1:1). Hittite Journal of Science and Engineering, Cilt: 6 - Sayı: 1, 63–68. https://ajindex.com/articles/537992
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