The effects of maternal age on assisted reproductive treatment outcomes

Key Findings & Data:In this study 569 patients who in vitro fertilization and embryo transfer was made between June 2000- January 2003 at ART department were evaluated retrospectively.

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Conclusion & Impact:This negative effect is significant in women > or =36 years of age.

🔬Design:Research Article

📍Scope:2000 Verileri

⚙️Variables:Domain Parameters

Abstract

To determine whether there is an effect of maternal age on treatment outcomes at assisted reproductive cycle. In this study 569 patients who in vitro fertilization and embryo transfer was made between June 2000- January 2003 at ART department were evaluated retrospectively. Patients were divided to four groups according to their ages as 40yThere were 208v(%36,5), 178v(%31,3), 142v(%25) and 41 v(%7,2) patients in each groups respectively. Collected mature oocytes and transferred embryo numbers were found significantly higher in 40years of age groups. Fertilization and implantation ratios show no difference according to age groups. There was no significant difference between age groups in pregnancy ratios. 40 years of age abortus ratio was found as %40. According to anembrionic, biochemistrical and ectopic pregnancy ratios we couldn't find difference between age groups.40 years of age group. The embryo quality according to age groups ,grade 1 and grade 2 embryo numbers were significantly decreasing as aging. Conclusion: There is a negative effect of maternal age on IVF -ET cycles success. This negative effect is significant in women > or =36 years of age.

Özet

Amaç:Yardımcı üreme sikluslarında maternal yaşın tedavi sonuçları üzerine etkisi olup olmadığının araştırılması planlandı. Çalışma Haziran 2000 - Ocak 2003 tarihleri arasında yardımcı üreme teknikleri (YÜT) bölümünde in vitro fertilizasyon ve embriyo transferi (IVF-ET) yapılan toplam 569 olgu üzerinde retrospektif olarak yapılmıştır. Hastalar yaş gruplarına göre 30 yaş ve altı, 31-35y, 36-40yaş ve 40 yaş üstü olmak üzere toplam 4 gruba ayrılmıştır. Toplanan matür oosit sayısı transfer edilen embriyo sayısı 36 yaş altında anlamlı olarak yüksek bulunmuştur. 36-40y ve >40y grupları arasında farklılık yoktur. Fertilizasyon ve implantasyon oranları yaş gruplarına göre farklılık göstermemiştir. Yaş grupları ile gebelik oranları arasında anlamlı farklılık yoktur.

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Cite This Article

SEZER, H., YALTI, S., GÜRBÜZ, B., ÇAKAR, Y. (2022). The effects of maternal age on assisted reproductive treatment outcomes. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 44 - Sayı: 1, 13–16. https://ajindex.com/articles/535680

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