Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2004 / Cilt: 44 - Sayı: 1

Comparison of the body mass index and lipid profiles according to hypoglicemic agents types that used by diabetic patients

Diabetik hastaların kullandıkları hipoglisemik ilaç tiplerine göre beden kitle indeksi ve lipid profillerinin karşılaştırılması

Pages
9–12
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

TG levels were found significantly low in group 2 (p

📌 3 Key Takeaways

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Objective & Hypothesis:The effects of drugs on the lipid profiles and body mass index were investigated in type 2 diabetes mellitus (DM) patients whom were treated with oral anti-diabetic drugs and insulin previously for at least three months.
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Key Findings & Data:The records of 84 type 2 DM patients were divided into four groups; group 1 included 16 patients who were taking metformin, group 2 included 22 patients who were taking insulin, group 3 consisted of 29 patients who were taking sulfonylurea and group 4 consisted of 17 patients who were under diet therapy.
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Conclusion & Impact:TG levels were found significantly low in group 2 (p
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The effects of drugs on the lipid profiles and body mass index were investigated in type 2 diabetes mellitus (DM) patients whom were treated with oral anti-diabetic drugs and insulin previously for at least three months. The records of 84 type 2 DM patients were divided into four groups; group 1 included 16 patients who were taking metformin, group 2 included 22 patients who were taking insulin, group 3 consisted of 29 patients who were taking sulfonylurea and group 4 consisted of 17 patients who were under diet therapy. BMI of each patients were calculated and serum total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL), triglyceride (TG) levels were reviewed. TG levels were found significantly low in group 2 (p

Özet

Tedavi almakta olan tip 2 diabetes mellituslu hastalarda oral antidiabetik (OAD) ve insülin kullanımının hastaların lipid profilleri ve beden kitle indeksleri (BKİ) üzerindeki etkisi araştırıldı. Hastanemiz diabet polikliniğine başvurmuş toplam 84 tip 2 diabetes mellituslu hastanın takip kartları değerlendirilerek, aldıkları tedaviye göre 4 gruba ayrıldı. Bunların 16'sı metformin, 22' si insülin, 29'u sulfonilüre ve 17 tanesi de diyet tedavisi altındaydı. Hastaların beden kitle indeksleri (BKİ) hesaplandı ve serum total kolesterol, trigliserid (TG), yüksek dansiteli lipoprotein kolesterol (HDL-C), düşük dansiteli lipoprotein kolesterol (LDL-C), çok düşük dansiteli lipoprotein (VLDL) değerleri incelendi, insülin kullanan grupta trigliserid düzeyleri diğer gruplara göre anlamlı oranda düşük bulundu. BKİ ile HDL-C, VLDL ve TG arasında istatistiksel olarak anlamlı ilişki tespit edildi. Bu ilişki HDL-C ile BKİ arasında ters orantılıydı ve ileri derecede anlamlıydı (p

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Cite This Article

ÇELİK, S., YETKİN, Ö. D., AKKAN, Z., EYİNÇ, D. B., YILDIRIM, M. Y. (2022). Comparison of the body mass index and lipid profiles according to hypoglicemic agents types that used by diabetic patients. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 44 - Sayı: 1, 9–12. https://ajindex.com/articles/535669

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References (7)

  1. Altuntaş Y. Diabetes Mellitus'un tanımı, tanısı ve sınıflaması. Yenigün M. editör. Her yönüyle Diabetes Mellitus. istanbul: Nobel Tıp Kitapevi 2001
  2. Steiner G: Hyperlipidemia and atherosclerotic cardiovascular di'sease. In 'Clinical Diabetes Mellitus 2000
  3. Betteridge DJ: Lipid disorders in diabetes mellitus. In 'Textbook of Diabetes. J Pickup. G Williams eds. Blackwell Science Ltd. 2nd ed.New York, 1997
  4. The absence of a glycemic threshold for the development of long-term complications: the perspective of the Diabetes Control and Complications Trial. Diabetes. 1996:45:1289-98. 5.Parving HH, Gall MA, Skott MA, Jorgensen HE, Lokkegaard H, Jorgensen F, et al. Prevalance and causes of albuminuria in nonmsulindependent diabetic Patients. Kidney Int. 1992:41:758-62. 6.Kelley DE. Effects of weight loss on glucose homeostasis in NIDDM. Diabetes Rev. 1995:3:366-77. 7.Taskinen MR, Kuusi T Helve E, et al: Insulin therapy induces anti-atherogenic changes of serum lipoprotein in noninsülin-dependent diabetes. Atherosclerosis 1988:68. 8.AbramsJJ, Ginsberg H, Grundy SM: Metabolism of cholesterol and plasma triglycerides in nonketotic diabetes mellitus. Diabetes 1982:31:903-910. 9.Walden CE, Knopp RH, Wahl PW, et at: Sex differences in the effect of diabetes mellitus on lipoprotein triglyceride and cholesterol concentrations. N Engl J Med 1984:311:953-959. 10.Abhimanyu Garg M BBS: Dyslipoproteinemia and diabetes. Endoc and Met Clin 1978
  5. 1998, 11.Gibbons GF: Hyperlipidemia of diabetes. Clin Sci 1986:71:477-86. 12.Heaven GM: NIDDM, abnormal lipoprotein metabolism, and atherosclerosis. Metabolism 1987
  6. Ginsberg HN: Very low density lipoprotein metabolism in diabetes mellitus. Diabetes Metab Rev 1987:3:571-89. 14.Taskinen M-R: Lipoprotein lipase in diabetes. Diabetes Metab Rev 1987:3:551-70. 15.StalenhoefA. F. H., Demacker P. N. M., Lutterman, J. A., van't LaarA. Ibid, 1978
  7. Agardh C-D, Nilsson- Ehle P. Schersten B: Improvement of the plasma lipoprotein pattern after institution of insulin treatment in diabetes meliitus. Diabetes Care 1982:5:322-25. 17.Lisch HJ, Sailer S: Lipoprotein patterns in diet, sulfonylurea and insulin treated diabetics. Diabetologia 1981:20:118-122. 18.Calvert GD, Graham JJ, Mannik T. et al: Effects of therapy on plasma high density lipoprotein cholesterol concentration in diabetes mellitus. Lancet 1978:2:66-68. 19.Howard BV, Xiaoren P. Harper I. et al: Effect of sultonylurea therapy on plasma lipids a