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Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2016 / Cilt: 56 - Sayı: 1

ORGANOFOSFAT İNTOKSİKASYONUNDA ATİPİK BİR PREZENTASYON: EKSTRAPİ- RAMİDAL BULGULAR

AN ATYPICAL PRESENTATION of ORGANOPHOSPHATE INTOXICATION: EXTRAPYRAMIDAL SIGNS

Bengü GÜLHAN AYDIN
Işıl Özkoçak TURAN
Bülent Serhan YURTLU
Volkan HANCI
Pages
52–55
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We aim to present an acute organophosphate intoxication case who was admitted to the emergency unit with extrapyramidal symptoms

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Organophosphate intoxications may cause serious clinical results as the activation mechanism of organophosphates is via the inhibition of cholinesterase enzyme.
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Key Findings & Data:Even if muscarinic and nicotinic symptoms are seen in the acute phase of intoxication, extrapyramidal symptoms are very rare.
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Conclusion & Impact:We aim to present an acute organophosphate intoxication case who was admitted to the emergency unit with extrapyramidal symptoms
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Organophosphate intoxications may cause serious clinical results as the activation mechanism of organophosphates is via the inhibition of cholinesterase enzyme. Even if muscarinic and nicotinic symptoms are seen in the acute phase of intoxication, extrapyramidal symptoms are very rare. We aim to present an acute organophosphate intoxication case who was admitted to the emergency unit with extrapyramidal symptoms

Özet

Organofosfatların etki mekanizması kolinesteraz enzim inhibisyonu yoluyla olduğundan organofosfat zehirlenmeleri ciddi klinik sonuçlara neden olabilir. Zehirlenmenin akut döneminde muskarinik ve nikotinik semptomlar görülse de ekstrapiramidal bulgulara nadiren rastlanır. Biz bu olgu sunumunda acil servise ekstrapiramidal semptomlarla başvuran bir akut organofosfat zehirlenmesi olgusunu sunmayı amaçladık

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Cite This Article

AYDIN, B. G., TURAN, I. Ö., YURTLU, B. S., HANCI, V. (2022). ORGANOFOSFAT İNTOKSİKASYONUNDA ATİPİK BİR PREZENTASYON: EKSTRAPİ- RAMİDAL BULGULAR. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 56 - Sayı: 1, 52–55. https://ajindex.com/articles/535280

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References (13)

  1. London L, Flisher AJ, Wesseling C, Mergler D, Kromhout H. Suicide and exposure to organophosphate insecticides: cause or effect? Am J lnd Med. 2005; 47:308-321.
  2. Berger AR, Schaumburg HH. Effect of occupational and environmental agents on the nervous system. ln Bradley WG, Editor. Neurology in Clinical Practice. Boston:Butterworth-Heinemann; 1996:p.1389-401.
  3. Kamel F, Hoppin JA. Association of pesticide exposure with neurologic dysfunction and disease. Environ Health Perspect. 2004;112:950-958.
  4. Sahin HA, Sahin I, Arabaci F. Sociodemographic factors in organophosphate poisonings: a prospective study. Hum Exp Toxicol 2003;22:349-353. Dharmani C, jaga K. Epidemiology of acute organop- hosphate poisoning in hospital emergency room pa- tients.Rev Environ Health. 2005;20:215-232.
  5. Senanayake N, Karalliedde L. Neurotoxic effects of or- ganophosphorus insecticides. An intermediate syndro- me. N Engl J Med.1987;316:761-763.
  6. Hsieh BH, Deng JF, Ger J, Tsai WJ. Acetylcholinestera- se inhibition and the extrapyramidal syndrome: a review of the neurotoxicity of organophosphate. Neurotoxico- logy 2001;22:423-427.
  7. Senanayake N, Sanmuganathan PS. Extrapyramidal manifestation complicating organophosphorus insecti- cide poisoning.Hum Exp Toxicol. 1995;14;500-504.
  8. Hashim HZ, Wan Musa WR, Nqiu CS, Won Yahya WN, Tan HJ, İbrahim N. Parkinsonism complicating acute or- ganophosphate insecticide poisoning. Ann Acad Med Singapore 2011;40:150-1511
  9. Sarıtaş A, Çakır Z, Aslan Ş. Organofosfat ve karbamat zehirlenmeleri. EAJM 2007;39:55-59.
  10. Robey WC, Meggs WJ. lnsecticides, Herbicides and Rodenticides. ln Judith E. Tintinally, Editor Emergency Medicine. 5 th ed. New York: McGraw-Hill;2004: p.333- 343 Lotti M. Central toxicity and behavioural effects of anti- cholinesterases.In Ballantyne B, Marrs TC (eds). Clinical and Experimental Toxicology of Organophosphates and Carbamates. Oxford: Butterworth-Heinemann,1992.
  11. Bhatt MH, Elias MA, Mankodi AK. Acute and reversible parkinsonism due to organophosphate pesticide intoxi- cation. Neurology 1999;52:1467-1471.
  12. Muller-Vahl KR, Kolbe H, Dengler R. Transient severe parkinsonism after acute organophosphate poisoning. J Neurol Neurosurg Psychiat. 1999:66:253-254.
  13. Nakamagoe K, Watanabe M, Tekeda T, Mizutani T, Ta- maoka A. Parkinsonism with organophosphate poiso- ning. BMJ case report 2009. pii: bcr04.2009.1766. doi: 10.1136/bcr.04.2009.1766. Shahar E, Bentur Y, Bar-Joseph G, Cahana A, Hers- hman E. Extrapyramidal Parkinsonism Complicating Acute Organ