Journals / Hamidiye Medical Journal / 2021 / Cilt: 2 - Sayı: 2

Risk Factors for Pulmonary Embolism in Patients with Lung Cancer and Effects of Pulmonary Embolism on Prognosis

Akciğer Kanserli Hastalarda Pulmoner Emboli için Risk Faktörleri ve Pulmoner Embolinin Prognoza Etkileri

Pages
50–56
Publication Date
2022-10-19
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The mean survival time was significantly longer in the non-PE group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background: Malignancy is an important risk factor for venous thromboembolism.
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Key Findings & Data:Materials and Methods: The study’s data came from lung cancer patients who were followed up between January 2012 and May 2017.
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Conclusion & Impact:The mean survival time was significantly longer in the non-PE group (p
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: Malignancy is an important risk factor for venous thromboembolism. Lung cancer is one of the frequently determined cancer associated with pulmonary embolism (PE). In our research, we compared lung cancer patients diagnosed with PE at the same period and lung cancer patients without PE. Besides, we investigated the risk factors that could predict PE in lung cancer patients, whether survival was different between patients who were diagnosed with PE incidentally and those who were diagnosed proactively. Materials and Methods: The study’s data came from lung cancer patients who were followed up between January 2012 and May 2017. A total of 235 patients with a thoracic angiographic computed tomography scan and/or ventilation/perfusion scintigraphy were included in the study. 109 patients with PE and 126 patients without a PE diagnosis were reported. Demographic information, lung cancer types and stages, time between lung cancer and PE, and survival were all recorded. Results: The PE group’s median age was 61 years (45-82 years), while the non-PE group’s median age was 61 years (35-83 years). Adenocarcinoma was the most common histological form in the PE population, with higher leukocyte and C-reactive protein (CRP) levels and lower hemoglobin levels. The PE group had a mean survival time of 20.1±1.6 months, while the non-PE group had a mean survival time of 36.5±2.9 months. The mean survival time was significantly longer in the non-PE group (p

Özet

Amaç: Malignite, venöz tromboembolizm için önemli risk faktörlerinden biridir. Akciğer kanseri, pulmoner emboli (PE) ile en sık ilişkili malignitelerden biridir. Çalışmamızda aynı dönemde PE tanısı almış akciğer kanseri hastaları ile PE’si olmayan akciğer kanseri hastalarını karşılaştırdık ve PE’nin sağkalım üzerindeki etkisini göstermeyi amaçladık. Ayrıca akciğer kanseri hastalarında PE’yi öngörebilecek risk faktörlerini ve tesadüfen PE tanısı alan hastalarda ve diğerlerinde sağkalımda bir fark olup olmadığını araştırdık. Gereç ve Yöntemler: Çalışmadaki veriler Ocak 2012-Mayıs 2017 tarihleri arasında hastanemizde izlenen akciğer kanseri hastalarından elde edildi. Toraks anjiyo bilgisayarlı tomografi taraması ve/veya ventilasyon/perfüzyon sintigrafisi olan 235 hasta dahil edildi. Toraks anjiyo bilgisayarlı tomografi taraması ve ventilasyon/perfüzyon sintigrafisi ile yapılan incelemelerde PE tanısı alan 109, PE tanısı olmayan 126 hasta belirlendi. Demografik veriler, akciğer kanserinin tipleri ve evreleri, akciğer kanseri ile PE arasındaki süre ve sağkalım kaydedildi. Bulgular: PE grubunun ortanca yaşı 61 (45-82) yıl ve PE olmayan grubun ortanca yaşı 61 yıl idi (35-83). PE grubunda en sık görülen histolojik tipin adenokarsinom olduğu, lökosit ve C-reaktif protein (CRP) değerlerinin daha yüksek, hemoglobin değerlerinin daha düşük olduğu görüldü. Akciğer kanseri tanısı konulduktan sonraki ortalama sağkalım süreleri karşılaştırıldığında; PE grubunun ortalama sağkalım süresi 20,1±1,6 ay ve PE olmayan grubun ortalama sağkalım süresi 36,5±2,9 aydı. Ortalama sağkalım süresi PE olmayan grupta anlamlı olarak daha uzundu (p

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Cite This Article

Polat, G., Tatar, D., Deniz, S., Ayrancı, A., Çimen, P., Katgı, N. (2022). Risk Factors for Pulmonary Embolism in Patients with Lung Cancer and Effects of Pulmonary Embolism on Prognosis. Hamidiye Medical Journal, Cilt: 2 - Sayı: 2, 50–56. https://ajindex.com/articles/533857

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