Journals / Hamidiye Medical Journal / 2021 / Cilt: 2 - Sayı: 1

Effects of Smoking on Acute Hypobaric Hypoxia Tolerance

Sigara Kullanımının Akut Hipobarik Hipoksi Toleransı Üzerine Etkisi

Pages
37–42
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The influences of carboxyhemoglobin on hypoxia tolerance might be better observed at lower altitudes if this study would have been redone at 18,000 and 25,000 simulated altitudes.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: Smoking may impair oxygen transport ability of blood and airway destructions might be seen in long term smokers.
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Key Findings & Data:After 1-3 cigarette smoking, it leads to a rise in carboxyhemoglobin level in blood, and it has a negative effect such as taking extra 5,000-8,000 feet altitude.
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Conclusion & Impact:The influences of carboxyhemoglobin on hypoxia tolerance might be better observed at lower altitudes if this study would have been redone at 18,000 and 25,000 simulated altitudes.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: Smoking may impair oxygen transport ability of blood and airway destructions might be seen in long term smokers. After 1-3 cigarette smoking, it leads to a rise in carboxyhemoglobin level in blood, and it has a negative effect such as taking extra 5,000-8,000 feet altitude. Thus, it is thought that smoking before or in-flight may contribute to altitude hypoxia. The objective of this study was to evaluate the effects of smoking on acute hypobaric hypoxia tolerance at 30,000 ft. simulated altitude. Materials and Methods: This study was planned prospectively, and a standardized survey that consisted of smoking status and demographic characteristics of subjects was applied before the procedures. Aircrews are exposed to high altitude during “Hypobaric Hypoxia Training” in an altitude chamber. Pulse oximeter measurements were done to analyze oxygen saturations during different stages of the hypoxia trainings. Results: Seventy eight male healthy aircrews were included in this study. Twenty five (32.1%) of subjects stated that they were currently smoking (4.9±2.6 years). Hypoxic pulse oximeter mean values of the Nonsmoker Group were higher than those of the Smoker Group (p>0.05). The three most frequently checked symptoms were numbness, tingling and perspiration among all participants. Flushing was the most frequent symptom in the Smoker Group while numbness was the most frequent symptom in the Nonsmoker Group. Both early and late symptoms among pilots were higher in the Smoker Group (p>0.05). More symptoms were checked among smokers during hypoxia exposure in this study(p>0.05). Conclusion: Our results might be attributed to hypoxia sensitiveness of smokers, and the use of tobacco products by aviation personnel was considered to be disadvantage in aviation environment. Because of this, doctors who carry out aviation examinations and practise preventive medicine in aviation field should be aware of the importance of this issue. The influences of carboxyhemoglobin on hypoxia tolerance might be better observed at lower altitudes if this study would have been redone at 18,000 and 25,000 simulated altitudes.

Özet

Amaç: Sigara kullanımı kanda oksijen transportunu bozduğu gibi uzun dönem kullanımında solunum yolu harabiyetine neden olur. Bir ile üç arasında sigara içimi kanda karboksihemoglobin seviyelerini artırır ve 5.000-8.000 ft. daha yüksek irtifada bulunuyormuş gibi negatif bir etki oluşturur. Böylece, uçuştan hemen önce veya uçuş sırasında sigara içilmesi irtifa hipoksisini arttırabilir. Bu çalışmanın amacı 30.000 ft. simüle irtifada oluşan hipobarik hipoksi toleransına sigara kullanımının etkilerinin değerlendirilmesidir. Gereç ve Yöntemler: Prospektif planlanan bu çalışmaya başlanmadan önce kişilerin demografik özelliklerini ve sigara kullanım durumlarını sorgulayan bir anket çalışması uygulandı. İrtifa odasında icra edilen hipobarik hipoksi eğitimi sırasında havacılık personelleri yüksek irtifaya maruz kalmaktadırlar. Çalışmamızda, hipoksi eğitiminin çeşitli safhalarında kan oksijen satürasyon değişimlerinin analizi için pulse oksimetre ölçümleri yapılmış ve ölçüm sonuçları sigara kullanım durumlarına göre karşılaştırılmıştır. Bulgular: Bu çalışmaya 78 sağlıklı erkek havacılık personeli dahil edildi. Katılımcılardan 25’i (%32,1) sigara kullandığını belirtmiştir (4,9±2,6 yıl). Sigara kullanmayanların hipoksik pulse oksimetre ortalamaları sigara kullananlara göre yüksek bulunmuştur (p>0,05). Tüm katılımcılar arasında en sık işaretlenmiş olan üç semptom uyuşma, karıncalanma ve terlemedir. Sigara kullanan grupta en sık işaretlenen semptom ateş basması iken sigara içmeyen grupta en sık işaretlenen bulgu uyuşma olmuştur. Katılımcılar arasında

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Cite This Article

TAŞÇI, C., ERCAN, E., İLBASMIŞ, M. Ş. (2022). Effects of Smoking on Acute Hypobaric Hypoxia Tolerance. Hamidiye Medical Journal, Cilt: 2 - Sayı: 1, 37–42. https://ajindex.com/articles/533865

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