Journals / Hamidiye Medical Journal / 2021 / Cilt: 2 - Sayı: 2

Is There Any Difference in the Predictive Findings for VUR in Different Age Groups? Evaluation of VCUG and USG Examinations in 539 Children with Febrile Urinary Tract Infection

Farklı Yaş Gruplarında VUR için Prediktif Bulgularda Fark Var Mıdır? Ateşli İdrar Yolu Enfeksiyonu Olan 539 Çocuğun USG ve VCUG Muayenelerinin Değerlendirilmesi

Pages
57–63
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Thinned parenchymal and moderate to severe hydronephrosis were significantly correlated with the presence of reflux for children older than 5 years.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: The clinical presentation and the course of vesicoureteral reflux (VUR) vary according to age.
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Key Findings & Data:All guidelines for the evaluation of urinary tract infections (UTIs) focus on infants under 2 years of age.
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Conclusion & Impact:Thinned parenchymal and moderate to severe hydronephrosis were significantly correlated with the presence of reflux for children older than 5 years.
🔬Design:Review & Systematic Survey
📍Scope:2016 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: The clinical presentation and the course of vesicoureteral reflux (VUR) vary according to age. All guidelines for the evaluation of urinary tract infections (UTIs) focus on infants under 2 years of age. To determine which factors might predict the presence of VUR among different age groups, we retrospectively reviewed the factors including patient characteristics and renal bladder ultrasonography (RBUS) and findings obtained from voiding cystourethrography (VCUG) examinations in a children’s hospital. Materials and Methods: RBUS and VCUG reports of 539 patients performed for febrile UTI in 2016 were reviewed. The associations between RBUS findings and abnormalities found in VCUG findings were investigated. The predictive findings of RBUS for VUR were evaluated among three age groups (0-2 y, 2-5y, and >5 years). Results: In total, 368 girls (68.3%) and 171 boys (31.7%) with a mean age of 6.29+4.18 years were evaluated. RBUS results were abnormal in 78.5% of patients. VUR was reported in 284 (52.7%) patients who underwent a VCUG. A significant result in the multivariate analysis of patients at 0-2 years of age was that RBUS renal parenchymal thinning was a predictor of VUR. Patients over 5 years of age were found to have a higher risk of VUR when patients had moderate to severe hydronephrosis accompanying parenchymal thinning. Conclusion: In children younger than 2 years, thinned parenchymal thickness helped predict the findings for VUR. Predicting the presence of VUR made no significant difference among the RBUS findings in children at the age of 2-5 years. Thinned parenchymal and moderate to severe hydronephrosis were significantly correlated with the presence of reflux for children older than 5 years.

Özet

Amaç: Vezikoüreteral reflünün (VUR) klinik prezentasyonu ve seyri yaşa göre değişim göstermektedir. İdrar yolu enfeksiyonlarının (İYE) değerlendirilmesi için yapılmış tüm kılavuzlar 2 yaş altındaki çocuklar üzerinde yoğunlaşmaktadır. Değişik yaş grupları arasında VUR düşündürecek faktörleri tespit etmek amacıyla bir çocuk hastanesindeki hasta özellikleri, üriner ultrason (RBUS) ve voiding sistoürerografi (VCUG) bulguları dahil olmak üzere retrospektif olarak değerlendirildi. Gereç ve Yöntemler: 2016’da ateşli İYE nedeniyle 539 hastaya yapılmış olan RBUS ve VCUG raporları değerlendirildi. RBUS bulguları ve anormal VCUG bulguları arasındaki ilişki araştırıldı. RBUS’de görülen, VUR düşündürecek bulgular üç yaş grubu arasında değerlendirildi (0-2 yaş, 2-5 yaş, ve >5 yaş). Bulgular: Ortalama yaşı 6,29+4,18 yıl olan toplamda 386 kız ve 171 erkek değerlendirildi. Sıfır-iki yaş arası hastalarda yapılan çok değişkenli analizde, RBUS’de böbrekte parankimal incelme görülmesi VUR açısından anlamlı olarak sonuçlandı. Orta-ileri derece hidronefroza eşlik eden parankimal incelmesi olan 5 yaş ve üzeri hastalarda VUR riskinin daha yüksek olduğu görüldü. Sonuç: Parankim kalınlığının incelmesi 2 yaş altındaki hastalarda VUR düşünülmesinde yardımcı olmuştur. İki-beş yaş arası çocuklarda VUR düşünülmesi RBUS bulguları arasında anlamlı değişiklik oluşturmamıştır. Beş yaştan büyük çocuklarda VUR varlığı ile incelmiş parankim ve orta-ileri derece hidronefroz varlığı arasında anlamlı ilişki olduğu görülmüştür

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Cite This Article

Güney, D., Bostancı, S. A., Tiryaki, H. T., Demirtaş, G. (2022). Is There Any Difference in the Predictive Findings for VUR in Different Age Groups? Evaluation of VCUG and USG Examinations in 539 Children with Febrile Urinary Tract Infection. Hamidiye Medical Journal, Cilt: 2 - Sayı: 2, 57–63. https://ajindex.com/articles/533864

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