Journals / Hamidiye Medical Journal / 2022 / Cilt: 3 - Sayı: 1

Intrahepatic Cholestasis and Adverse Perinatal Outcomes in the Third Trimester: A 10-year Case-control Study

Üçüncü Trimesterde İntrahepatik Kolestaz ve Olumsuz Perinatal Sonuçlar: 10 Yıllık Bir Olgu Kontrol Çalışması

Pages
40–45
Publication Date
2022-10-19
DOI
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Results: There was no significant difference in terms of family history, fetal gender, or the presence of meconium in the amniotic fluid between the groups (p>0.05) except cesarean rates were significantly higher in ICP group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background: To evaluate the perinatal outcomes in women whom developed intrahepatic cholestasis of pregnancy (ICP).
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Key Findings & Data:Materials and Methods: Medical records of 76 patients who were followed up in a tertiary center due to ICP between January 2010 and December 2019 were evaluated retrospectively.
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Conclusion & Impact:Results: There was no significant difference in terms of family history, fetal gender, or the presence of meconium in the amniotic fluid between the groups (p>0.05) except cesarean rates were significantly higher in ICP group (p
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: To evaluate the perinatal outcomes in women whom developed intrahepatic cholestasis of pregnancy (ICP). Materials and Methods: Medical records of 76 patients who were followed up in a tertiary center due to ICP between January 2010 and December 2019 were evaluated retrospectively. Women with ICP (n=76) and age matched controls (n=228) were included to our study. Bile acid (BA) values could be reached in 42 of 76 patients. Results: There was no significant difference in terms of family history, fetal gender, or the presence of meconium in the amniotic fluid between the groups (p>0.05) except cesarean rates were significantly higher in ICP group (p

Özet

Amaç: Bu çalışmadaki amacımız gebeliğinde intrahepatik kolestaz (ICP) gelişen kadınlarda perinatal sonuçları değerlendirmektir. Gereç ve Yöntemler: Ocak 2010 ile Aralık 2019 tarihleri arasında üçüncü basamak bir merkezde ICP nedeniyle izlenen 76 hastanın tıbbi kayıtları geriye dönük olarak değerlendirildi. ICP’si mevcut olan kadınlar (n=76) ve aynı yaştaki kontroller (n=228) çalışmaya dahil edildi. Safra asidi (SA) değerlerine 76 hastanın 42’sinde ulaşılabildi. Bulgular: Gruplar arasında aile öyküsü, fetal cinsiyet ve amniyotik sıvıda mekonyum varlığı açısından anlamlı fark yoktu (p>0,05), ama sezaryen oranları ICP’li grupta anlamlı olarak yüksekti (p

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Cite This Article

Ateş, S., Varol, F., Sayın, C., Yener, C., Erbilen, E. A. (2022). Intrahepatic Cholestasis and Adverse Perinatal Outcomes in the Third Trimester: A 10-year Case-control Study. Hamidiye Medical Journal, Cilt: 3 - Sayı: 1, 40–45. https://ajindex.com/articles/533840

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