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Journals / Hacettepe Journal of Biology and Chemistry / 2018 / Cilt: 46 - Sayı: 3

PVA Nanofibers Including Biopolymer-grafted Copolymer for Potential Biomedical Applications

Potansiyel Biyomedikal Uygulamalar için BiyopolimerYamalanmış Kopolimer İçeren PVA Nanofiberler

Murat ŞİMŞEK
Pages
381–389
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Nanofibers exhibit low cytotoxicity and necrotic effect for MC3T3-E1 preosteoblast cells.

📌 3 Key Takeaways

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Objective & Hypothesis:Multifunctional nanofibers were fabricated by electrospinning of polyvinyl alcohol/octadecylamine montmorillonite layered silicate nanocomposite as a matrix polymer and amphiphilic copolymer-g-biopolymer (polylactic acid, PLA) as a biocompatible partner polymer.
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Key Findings & Data:Crystal structure of the nanofibers significantly changed due to in situ phase separation processing via different chemical and physical interfacial interactions.
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Conclusion & Impact:Nanofibers exhibit low cytotoxicity and necrotic effect for MC3T3-E1 preosteoblast cells.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Multifunctional nanofibers were fabricated by electrospinning of polyvinyl alcohol/octadecylamine montmorillonite layered silicate nanocomposite as a matrix polymer and amphiphilic copolymer-g-biopolymer (polylactic acid, PLA) as a biocompatible partner polymer. Crystal structure of the nanofibers significantly changed due to in situ phase separation processing via different chemical and physical interfacial interactions. Relative high thermal stability, high first melting and low crystallinity were observed for the matrix/polymer nanofibers. Nanofibers exhibit low cytotoxicity and necrotic effect for MC3T3-E1 preosteoblast cells.

Özet

Çok fonksiyonlu nanofiberler matris polimer olarak polivinil alkol/oktadesilamin montmorillonit tabakalı silikat nanokompozitin ve biyouyumlu partner polimer olarak amfifilik kopolimer-g-biyopolimer’in (polilaktik asit, PLA) elektroeğrilmesi ile üretilmişlerdir. Nanofiberlerin kristal yapısı farklı kimyasal ve fiziksel arayüzey etkileşimler yoluyla ortaya çıkan in situ faz ayrımı prosesi sebebiyle önemli seviyede gelişmiştir. Nanofiberler MC3T3-E1 preosteoblast hücreleri varlığında düşük seviyede sitotoksik ve nekrotik etki sergilemişlerdir.

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Cite This Article

ŞİMŞEK, M. (2022). PVA Nanofibers Including Biopolymer-grafted Copolymer for Potential Biomedical Applications. Hacettepe Journal of Biology and Chemistry, Cilt: 46 - Sayı: 3, 381–389. https://ajindex.com/articles/529083

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References (12)

  1. Z.M.O. Rzayev, B. Şenol, B.E. Denkbaş, Functional copolymer/organo-montmorillonite nanoarchitectures. IX. Synthesis and nanostructure– morphology–thermal behaviour relationships of poly[(maleic anhydride)-alt-(acrylic acid)]/organomontmorillonite nanocomposites, Polym. Int., 60 (2011) 1446-1454.
  2. P.R. Rudolf, B.G Landes, Two-dimensional X-Ray diffraction and scattering of microcrystalline and polymeric materials, Spectroscopy, 9 (1994) 22-33.
  3. Z.M.O. Rzayev, K. Salimi, Ö.Eğri, E. Pişkin, Functional copolymer/organo-MMT nanoarchitectures. XIX. Nanofabrication and characterization of poly(MA-alt1-octadecene)-g-PLA layered silicate nanocomposites with nanoporous core–shell morphology, Polym. Advan. Technol., 25 (2014), 294–306.
  4. Z.M.O. Rzayev, D. Erdönmez, K. Erkan, M.Şimşek, U. Bunyatova, Functional Copolymer/OrganoMMT Nanoarchitectures. XXII. Fabrication and Characterization of Antifungal and Antibacterial Poly (Vinyl Alcohol-co-Vinyl Acetate/ODA-MMT/ AgNPs Nanofibers and Nanocoatings by eSpinning and c-Spinning Methods, Int. J. Polym. Mater. PO., 64 (2015), 267–278.
  5. M.A. Attawia, K.M. Herbert, C.T. Laurencin, Osteoblast-like cell adherance and migration through 3-dimensional porous polymer matrices, Biochem. Bioph. Res. Co., 213 (1995) 639-644.
  6. J.C. Meredith, E.J. Amis, Lcst phase separation in biodegradable polymer blends: Poly(d,l-lactide) and poly(epsilon-caprolactone), Macromol. Chem. Phys., 201 (2000) 733-739.
  7. S.T.C. Lin, D. Bhattacharyya, S. Fakirov, J. Cornish, Novel organic solvent free micro-/nano-fibrillar, nanoporous scaffolds for tissue engineering, Int. J Polym. Mater. Po., 63 (2014) 416-423.
  8. L. Lin, W. Z. Gong, S. Y. Wanga, Hollow PET fibers containing silver particles as antibacterial materials, J. Text. I., 102 (2011) 419-423.
  9. I.M. El-Sharbiny, S. Yahia, M.A. Messiery, M.F. Reichac, Preparation and physicochemical characterization of new nanocomposites based on -type chitosan and nano-hydroxyapatite as potential bone substitute materials, Int. J Polym. Mater. Po., 63 (2014) 213-220.
  10. K.E. Strawhecker, E. Manias, Structure and properties of poly(vinyl alcohol)/Na montmorillonite nanocomposites, Chem. Mater., 12 (2000) 2943-2949.
  11. H.W. Lee, M.R. Karim, H.M. Ji, Electrospinning fabrication and characterization of poly (vinyl alcohol)/montmorillonite nanofiber mats, J. Appl. Polym. Sci., 113 (2009) 1860-1867.
  12. K.H. Hong, J.L. Park, I.H. Sul, J.H. Youk, T.J. Kang, Preparation of antimicrobial poly (vinyl alcohol) nanofibers containing silver nanoparti