Journals / Hacettepe Journal of Biology and Chemistry / 2022 / Cilt: 50 - Sayı: 2

Cytotoxic Activity Studies of p-Chloro and Fluoro Substituted Formazan Derivatives on Lung and Prostate Cancer Cell Lines

Pages
151–156
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Particularly, compound FF having p-fluoro had more antiproliferative activity compared to CF in both studied cancer cell lines.

📌 3 Key Takeaways

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Objective & Hypothesis:The cytotoxic activity properties of formazan derivatives (CF and FF) bearing halogen chlorine and fluorine groups placed at para position in 1-phenyl ring have been systematically investigated in this work.
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Key Findings & Data:The synthesized two compounds were tested as anticancer agents against human cancerous cell lines for 48 h.
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Conclusion & Impact:Particularly, compound FF having p-fluoro had more antiproliferative activity compared to CF in both studied cancer cell lines.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Formazan derivatives · cytotoxic activity · prostate cancer

Abstract

The cytotoxic activity properties of formazan derivatives (CF and FF) bearing halogen chlorine and fluorine groups placed at para position in 1-phenyl ring have been systematically investigated in this work. The synthesized two compounds were tested as anticancer agents against human cancerous cell lines for 48 h. The results obtained showed that these two compounds have cytotoxic effect towards screened cell lines. Particularly, compound FF having p-fluoro had more antiproliferative activity compared to CF in both studied cancer cell lines.

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Cite This Article

TÜRKOĞLU, G., AKKOÇ, S. (2022). Cytotoxic Activity Studies of p-Chloro and Fluoro Substituted Formazan Derivatives on Lung and Prostate Cancer Cell Lines. Hacettepe Journal of Biology and Chemistry, Cilt: 50 - Sayı: 2, 151–156. https://ajindex.com/articles/528920

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References (1)

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