Dergiler / Hacettepe Journal of Biology and Chemistry / 2022 / Cilt: 50 - Sayı: 2

Cytotoxic Activity Studies of p-Chloro and Fluoro Substituted Formazan Derivatives on Lung and Prostate Cancer Cell Lines

Sayfa
151–156
Yayın Tarihi
2022-10-17
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Particularly, compound FF having p-fluoro had more antiproliferative activity compared to CF in both studied cancer cell lines.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The cytotoxic activity properties of formazan derivatives (CF and FF) bearing halogen chlorine and fluorine groups placed at para position in 1-phenyl ring have been systematically investigated in this work.
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Temel Bulgular & Veri:The synthesized two compounds were tested as anticancer agents against human cancerous cell lines for 48 h.
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Sonuç & Katkı:Particularly, compound FF having p-fluoro had more antiproliferative activity compared to CF in both studied cancer cell lines.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Formazan derivatives · cytotoxic activity · prostate cancer

Abstract

The cytotoxic activity properties of formazan derivatives (CF and FF) bearing halogen chlorine and fluorine groups placed at para position in 1-phenyl ring have been systematically investigated in this work. The synthesized two compounds were tested as anticancer agents against human cancerous cell lines for 48 h. The results obtained showed that these two compounds have cytotoxic effect towards screened cell lines. Particularly, compound FF having p-fluoro had more antiproliferative activity compared to CF in both studied cancer cell lines.

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Bu Makaleye Atıf Yap

TÜRKOĞLU, G., AKKOÇ, S. (2022). Cytotoxic Activity Studies of p-Chloro and Fluoro Substituted Formazan Derivatives on Lung and Prostate Cancer Cell Lines. Hacettepe Journal of Biology and Chemistry, Cilt: 50 - Sayı: 2, 151–156. https://ajindex.com/articles/528920

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