Journals / Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research) / 2001 / Cilt: 25 - Sayı: 3-4

Retrograt dolgu maddesi olarak amalgamın sitotoksisitesi

The cytotoxic effect of amalgam as a retrograde filling material

Pages
61–65
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, a) zinc is the main cytotoxic element in amalgam b) freshly mixed, zinc free amalgams are not cytotoxic and can be used as root end filling materials.

📌 3 Key Takeaways

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Objective & Hypothesis:The purpose of this study is to evaluate the cytotoxicity of three amalgams (GS 80, Luxalloy, Permite C) as a retrograde filling material by using MTT colorimetric assay on L929 mouse fibroblasts.
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Key Findings & Data:GS 80 and Luxalloy showed no cytotoxicity at any dilution tested.
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Conclusion & Impact:In conclusion, a) zinc is the main cytotoxic element in amalgam b) freshly mixed, zinc free amalgams are not cytotoxic and can be used as root end filling materials.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The purpose of this study is to evaluate the cytotoxicity of three amalgams (GS 80, Luxalloy, Permite C) as a retrograde filling material by using MTT colorimetric assay on L929 mouse fibroblasts. GS 80 and Luxalloy showed no cytotoxicity at any dilution tested. However, Permite C showed cytotoxicity at 1/2 dilution. In conclusion, a) zinc is the main cytotoxic element in amalgam b) freshly mixed, zinc free amalgams are not cytotoxic and can be used as root end filling materials.

Özet

Bu çalışmanın amacı, L929 fare fibroblastlarında MTT colorimetric assay yöntemiyle, retrograt dolgu maddesi olarak kullanılan üç amalgamın (GS 80, Luxalloy, Permite C) sitotoksisitesini değerlendirmektir. GS-80 ve Luxalloy test edilen herhangi bir dilusyonda sitotoksisite göstermedi. Ancak, Permite-C 1/2 dilusyonda sitotoksisite gösterdi. Sonuç olarak, a) çinko amalgamda temel sitotoksisite elementidir b) yeni karıştırıldığında, çinkosuz amalgamlar sitotoksik değildir ve kök ucu dolgu maddesi olarak kullanılabilirler.

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Cite This Article

SERPER, A., GÜÇ, D., KİREMİTÇİ, A., DOĞAN, L., HÜRMÜZLÜ, F. (2022). Retrograt dolgu maddesi olarak amalgamın sitotoksisitesi. Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research), Cilt: 25 - Sayı: 3-4, 61–65. https://ajindex.com/articles/528674

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