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Journals / Güncel Retina Dergisi / 2022 / Cilt: 6 - Sayı: 2

Dominant Optic Atrophy

Dominant Optik Atrofi

Ebru Nevin ÇETİN
Emine ŞEKER ÜN
G. Ozan ÇETİN
Pages
88–91
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Currently there are no effective and approved therapies for DOA.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Dominant optic atrophy (DOA) is the most common hereditary optic neuropathy.
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Key Findings & Data:It characterized by insidious and progressive central visual loss.
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Conclusion & Impact:Currently there are no effective and approved therapies for DOA.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Dominant optic atrophy (DOA) is the most common hereditary optic neuropathy. It characterized by insidious and progressive central visual loss. Retinal ganglion cells and their descending axons selectively affected. Usually only the ocular system is affected but extraocular manifestations such as sensorineural hearing loss, myophathy, ataxia, peripheral neurophathy can occur. In the presence of extraocular involvement, the disease is called ‘’DOA plus syndrome’’. Currently there are no effective and approved therapies for DOA.

Özet

Dominant optik atrofi (DOA) en sık görülen herediter optik nöropatidir. Santral görme duyusunun sinsi ve progresif olarak azalmasıyla karakterizedir. Seçici olarak retina ganglion hücreleri ve aksonları etkilenir. Sıklıkla sadece okuler sistem etkilenir ancak sensörinöral işitme kaybı, miyopati, ataksi, periferal nöropati gibi eşlik eden ekstraokuler bulgular görülebilir. Extraokuler etkilenim varlığında hastalık ‘’DOA plus sendrom’’ olarak isimlendirilir. Günümüzde DOA ‘nin etkin ve onaylı bir tedavisi bulunmamaktadır.

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Cite This Article

ÇETİN, E. N., ÜN, E. Ş., ÇETİN, G. O. (2022). Dominant Optic Atrophy. Güncel Retina Dergisi, Cilt: 6 - Sayı: 2, 88–91. https://ajindex.com/articles/528134

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