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Journals / Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi / 2021 / Cilt: 27 - Sayı: 4

Effect of Cardiopulmonary Bypass on Tiiyodothyronine Functions in Congenital Cardiac Surgery

Konjenital Kalp Cerrahisinde Kardiyopulmoner Baypasın Triiyodotironin Fonksiyonları Üzerine Etkisi

Nurşen TANRIKULU
Nurgül YURTSEVEN
Esin EĞİLMEZ
Murat ÇİÇEK
Pages
261–265
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: According to T0 time T3 levels decreased statistically significantly in T2, T3, T4 and T5 periods, TSH levels decreased in T2, T3 and T4 while T4 levels were found to be statistically significantly lower at T2 and T3 periods than T1 time.(p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, the effect of open heart surgery on triiodothyronine (T3) functions was investigated in patients undergoing congenital cardiac surgery.
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Key Findings & Data:Methods: 30 patients who underwent elective congenital cardiac surgery were prospectively enrolled in the study.
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Conclusion & Impact:Results: According to T0 time T3 levels decreased statistically significantly in T2, T3, T4 and T5 periods, TSH levels decreased in T2, T3 and T4 while T4 levels were found to be statistically significantly lower at T2 and T3 periods than T1 time.(p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, the effect of open heart surgery on triiodothyronine (T3) functions was investigated in patients undergoing congenital cardiac surgery. Methods: 30 patients who underwent elective congenital cardiac surgery were prospectively enrolled in the study. Preoperatively (T0), during cardiopulmonary bypass (T1), postoperative 0th hour (T2), postoperative 1st day (T3), 2nd day (T4), 3rd day (T5) and 8 days (T6), free T3, thyroxine (T4) and thyroid stimulating hormone (TSH) values, intubation time, intensive care and hospital stay were recorded. Results: According to T0 time T3 levels decreased statistically significantly in T2, T3, T4 and T5 periods, TSH levels decreased in T2, T3 and T4 while T4 levels were found to be statistically significantly lower at T2 and T3 periods than T1 time.(p

Özet

Amaç: Bu çalışmada konjenital kardiyak cerrahiye gidecek hastalarda, açık kalp cerrahisinin triiyodotironin (T3) düzeylerine etkisi incelenmiştir. Yöntem: Elektif olarak konjenital kardiyak cerrahi geçiren 30 hasta prospektif olarak çalışmaya alınarak preoperatif (T0), pompa (T1), postoperatif 0.saat (T2), postoperatif 1. Gün (T3), 2. Gün (T4), 3. Gün (T5) ve 8. Gününde (T6), serbest T3, tiroksin (T4) ve tiroid uyarıcı hormon (TSH) değerleri, entübasyon zamanı, yoğun bakım ve hastanede kalış süreleri kaydedildi. Bulgular: T0 zamanına göre T3 düzeyleri T2, T3, T4 ve T5’de, TSH düzeyleri T2, T3 ve T4’de istatistiksel olarak anlamlı düşerken, T4 düzeylerinde T1 zamanına göre T2 ve T3 zamanındaki değerler istatiksel olarak anlamlı düşük bulundu. T3 düzeylerinde T0 zamanına göre T5 zamanındaki değişim ile entübasyon ve hastanede kalış süreleri arasında negatif korelasyon tespit edildi. Sonuç: Konjenital kardiyak cerrahi sonrası T3 seviyelerinin düştüğü ve düşük T3 seviyelerinin entübasyon ve hastanede kalış sürelerini olumsuz olarak etkilediği tespit edilmiştir.

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Cite This Article

TANRIKULU, N., YURTSEVEN, N., EĞİLMEZ, E., ÇİÇEK, M. (2022). Effect of Cardiopulmonary Bypass on Tiiyodothyronine Functions in Congenital Cardiac Surgery. Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi, Cilt: 27 - Sayı: 4, 261–265. https://ajindex.com/articles/525959

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