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Journals / Glokom Katarakt / 2019 / Cilt: 14 - Sayı: 4

Comparison of the Endothelial Protective Effect of Two Different Dispersive Viscoelastics During Phacoemulsifi cation Surgery

İki Farklı Dispersif Viskoelastik Maddenin Fakoemulsifi kasyon Esnasında Endotel Koruyucu Etkisinin Karşılaştırılması

Mustafa ATAŞ
Ayşe ÇİÇEK
Döndü Melek ULUSOY
Medine TEDİK
Necati DURU
Burhan BAŞKAN
İsmail AYDIN
Pages
175–179
Publication Date
2022-10-18
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Themean ECC decreased by 297 cells/mm2 (a 12.3 % loss) in the Viscoat group and by 343 cells/mm2(a 14.7 % loss) in the Endocoat group atpostoperative day 30, as is illustrated.There was no statistically signifi cant difference in ECC change at postoperative day 30 between the twogroups( p=0.21).Conclusion: The corneal endothelial protective effects of sodium hyaluronate % 3 (EndocoatR) and the combination of chondroitin sulfate4.0% and sodium hyaluronate % 3.0 (ViscoatR) during the phacoemulsifi cation were similar.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To compare the corneal endothelial protective effects of two different dispersive viscoelastics used in phacoemulsifi cation surgery(sodium hyaluronate % 3 [Endocoat®] and chondroitin sulfate % 4.0 - sodium hyaluronate % 3.0 combination [Viscoat®]).Material and methods: The study was comprised of two groups of patients : Both groups 1 and 2 were composed of 40 eyes of 40 patients onwhich Endocoat and Viscoat were used during phacoemulsifi cation, respectively.
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Key Findings & Data:Endothelial cell count (ECC) of all patients was measured atpostoperative days 1 and 30.
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Conclusion & Impact:Themean ECC decreased by 297 cells/mm2 (a 12.3 % loss) in the Viscoat group and by 343 cells/mm2(a 14.7 % loss) in the Endocoat group atpostoperative day 30, as is illustrated.There was no statistically signifi cant difference in ECC change at postoperative day 30 between the twogroups( p=0.21).Conclusion: The corneal endothelial protective effects of sodium hyaluronate % 3 (EndocoatR) and the combination of chondroitin sulfate4.0% and sodium hyaluronate % 3.0 (ViscoatR) during the phacoemulsifi cation were similar.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To compare the corneal endothelial protective effects of two different dispersive viscoelastics used in phacoemulsifi cation surgery(sodium hyaluronate % 3 [Endocoat®] and chondroitin sulfate % 4.0 - sodium hyaluronate % 3.0 combination [Viscoat®]).Material and methods: The study was comprised of two groups of patients : Both groups 1 and 2 were composed of 40 eyes of 40 patients onwhich Endocoat and Viscoat were used during phacoemulsifi cation, respectively. Endothelial cell count (ECC) of all patients was measured atpostoperative days 1 and 30. The changes in ECC at postoperative day 30 from baseline were compared between the two groups.Results: The preoperative mean ECCs were 2397±410 cells/mm2 in the Viscoat group and 2325±410 cells/mm2 in the Endocoat group. Themean ECC decreased by 297 cells/mm2 (a 12.3 % loss) in the Viscoat group and by 343 cells/mm2(a 14.7 % loss) in the Endocoat group atpostoperative day 30, as is illustrated.There was no statistically signifi cant difference in ECC change at postoperative day 30 between the twogroups( p=0.21).Conclusion: The corneal endothelial protective effects of sodium hyaluronate % 3 (EndocoatR) and the combination of chondroitin sulfate4.0% and sodium hyaluronate % 3.0 (ViscoatR) during the phacoemulsifi cation were similar.

Özet

Amaç: Fakoemülsifi kasyonda kullanılan iki farklı dispersif viskoelastik maddenin (sodyum hiyalüronat% 3 [Endocoat®] ve kondroidin sülfat % 4.0 - sodyum hiyalüronat % 3.0 kombinasyonu [Viscoat®]) kornea endotel koruyucu etkisini kıyaslamak. Gereç ve yöntem: Çalışma iki gruptan oluşmaktadır: Grup 1 fakoemülsifi kasyon esn asında Endocoat kullanılmış 40 hastanın 40 gözünü, Grup 2 fakoemülsifi kasyon esnasında Viscoat kullanılmış 40 hastanın 40 gözünü kapsamaktadır. Bütün hastaların endotel hücre sayısı (EHS) postoperatif 1. ve 30. günlerde ölçülmüştür. Preoperatif ve postoperatif 30. Gün arasındaki fark iki grup arasında kıyaslandı. Bulgular: Preoperatif ortalama EHS Grup 2’de 2397±410 hücre/mm2iken Grup 1 ‘de 2325±410 hücre/mm2 idi. Ortalama EHS Grup 2’de 297 hücre/mm2 (% 12.3 kayıp) miktarında azalırken, Grup 1’de 343 hücre/mm2 (% 14.7 kayıp) miktarında azalmıştır. Postoperatif 30. günde EHS’de gözlenen azalma iki grup arasında istatistiksel olarak anlamlı değildir ( p=0.21). Sonuç: Sodyum hiyalüronat% 3 [Endocoat®] ve kondroidin sülfat % 4.0 - sodyum hiyalüronat % 3.0 kombinasyonunun [Viscoat®] fakoemulsifi kasyonda kornea endotel koruyucu etkisi benzerdir.

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Cite This Article

ATAŞ, M., ÇİÇEK, A., ULUSOY, D. M., TEDİK, M., DURU, N., BAŞKAN, B., AYDIN, İ. (2022). Comparison of the Endothelial Protective Effect of Two Different Dispersive Viscoelastics During Phacoemulsifi cation Surgery. Glokom Katarakt, Cilt: 14 - Sayı: 4, 175–179. https://ajindex.com/articles/525762

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