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Journals / Glokom Katarakt / 2021 / Cilt: 16 - Sayı: 2

Investigation of the Acute Effects of Captopril Usage on Intraocular Pressure Before Cataract Surgery

Mert ŞİMŞEK
Ufuk ELGİN
Ali Mert KOÇER
Anıl GÜNGÖR
Pages
94–97
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

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Conclusion: This study concluded that the preoperative usage of captopril to lower the SABP in cataract cases had no acute effects on IOP; thus it can be safely used before the operation.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: In this study, our aim was to investigate the acute effects of captopril on intraocular pressure (IOP) in patients who received captopril preoperatively due to high systemic arterial blood pressure (SABP) before cataract surgery.
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Key Findings & Data:Material and Methods: This prospective and cross-sectional study included 28 eyes of 28 patients, who presented for cataract surgery and preoperatively received captopril (25 mg, sublingual) due to detection of high SABP between December, 2019 and April, 2020.
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Conclusion & Impact:Conclusion: This study concluded that the preoperative usage of captopril to lower the SABP in cataract cases had no acute effects on IOP; thus it can be safely used before the operation.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Purpose: In this study, our aim was to investigate the acute effects of captopril on intraocular pressure (IOP) in patients who received captopril preoperatively due to high systemic arterial blood pressure (SABP) before cataract surgery. Material and Methods: This prospective and cross-sectional study included 28 eyes of 28 patients, who presented for cataract surgery and preoperatively received captopril (25 mg, sublingual) due to detection of high SABP between December, 2019 and April, 2020. The IOP and anterior chamber depth (ACD) measurements were performed by Goldmann applanation tonometry and ocular biometry (Lenstar LS 900, Haag-Streit, USA) immediately before and 30 minutes after the drug intake. Wilcoxon test was used for statistical analysis. Results: The study included 28 patients (18 female, 10 male) mean age was 64.9±10.7 (49-85). Signifi cant decreases were observed in systolic blood pressure and mean arterial blood pressure after the drug intake (P˂0.001 and P=0.001, respectively). No signifi cant difference was found in diastolic blood pressure, ACD, and IOP parameters (P>0.05 for all). Conclusion: This study concluded that the preoperative usage of captopril to lower the SABP in cataract cases had no acute effects on IOP; thus it can be safely used before the operation.

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Cite This Article

ŞİMŞEK, M., ELGİN, U., KOÇER, A. M., GÜNGÖR, A. (2022). Investigation of the Acute Effects of Captopril Usage on Intraocular Pressure Before Cataract Surgery. Glokom Katarakt, Cilt: 16 - Sayı: 2, 94–97. https://ajindex.com/articles/525731

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