Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2021 / Cilt: 26 - Sayı: 1

Does Skin Bathing With Chlorhexidine Gluconate (2%) Affect the Carbapenem-resistant Enterobacteriaceaeand Vancomycin-resistant Enterococcus Colonization in Pediatric Intensive Care?

Klorheksidin Glukonat (%2) ile Cilt Yıkama Pediatrik Yoğun Bakımda Karbapenem-dirençli Enterobakter ve Vankomisin-Dirençli Enterokok Kolonizasyonunu Etkiler mi?

Pages
189–195
Publication Date
2022-10-17
DOI
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⚡ TL;DR(Too Long; Didn't Read)

We think that skin bathing with 2% CHG every other day in the PICU can be used as one of the resistant microorganism colonization and infection prevention methods.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococcus (VRE) colonization and infec-tions are important in the pediatric intensive care unit (PICU).
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Key Findings & Data:This study aimed to investigate the effect of a 2% chlorhexidine gluconate (CHG) bath on VRE and CRE colonization.Materials and Methods: Skin bathing was performed every other day with 2% CHG as of April 2019.
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Conclusion & Impact:We think that skin bathing with 2% CHG every other day in the PICU can be used as one of the resistant microorganism colonization and infection prevention methods.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococcus (VRE) colonization and infec-tions are important in the pediatric intensive care unit (PICU). This study aimed to investigate the effect of a 2% chlorhexidine gluconate (CHG) bath on VRE and CRE colonization.Materials and Methods: Skin bathing was performed every other day with 2% CHG as of April 2019. The frequency of CRE and VRE colonization pre and post-intervention was evaluated. Rectal swab samples were taken within 7 days before and after skin bathing with CHG. Besides, VRE and CRE spontaneously negation rates within 14 day periods were examined.Results: The number of CRE positive patients within the CHG group were detected as 10 (47.6%) before using CHG and as 8 (38%) after using (OR: 1.5, p= 0.131, 95% CI: 0.87-1.98). The number of VRE positive patients were detected within the CHG group as 15 (71.4%) before using CHG and as 10 (47.6%) after using (OR: 2.7, p= 0.044, 95% CI: 1.09-2.42). Also, when we compared the control group with the CHG group; there was no significant difference in CRE when comparing the negation rates (p= 0.804). There was a significant difference between the two groups in VRE (p= 0.048).Conclusion: It shows that performing skin bathing with 2% CHG every other day in the PICU significantly reduces VRE colonization but cannot decrease the risk of CRE colonization. We think that skin bathing with 2% CHG every other day in the PICU can be used as one of the resistant microorganism colonization and infection prevention methods.

Özet

Giriş: Karbapenem-dirençli Enterobakter (CRE) ve vankomisin-dirençli Enterokok (VRE) kolonizasyonu ve infeksiyonları çocuk yoğun bakım ünitesinde (ÇYBÜ) önemlidir. Bu çalışma, %2 klorheksidin glukonat (CHG) banyosunun VRE ve CRE kolonizasyonu üzerindeki etkisini araştırmayı amaçlamaktadır.Materyal ve Metod: Klorheksidin ile cilt banyosu, Nisan 2019 itibariyle gün aşırı %2 CHG ile gerçekleştirildi. Müdahale öncesi ve sonrası CRE ve VRE kolonizasyon sıklığı değerlendirildi. Rektal sürüntü örnekleri %2 CHG ile cilt banyosu başlanmadan önce 7 gün ve başlan-dıktan sonra 7 gün içinde alındı. Ayrıca, VRE ve CRE’nin 14 günlük periyotlar içerisinde kendiliğinden negatifleşme oranları incelendi.Bulgular: CHG grubundaki CRE pozitif hastaların sayısı, CHG kullanılmadan önce 10 (% 47.6) ve kullanıldıktan sonra 8 (%38) tespit edildi (OR: 1.5, p= 0.131,% 95 CI: 0.87-1.98). VRE pozitif hastalar, CHG kullanılmadan önce 15 (% 71.4) ve kullanıldıktan sonra 10 (%47.6) saptandı (OR: 2.7, p= 0.044, %95 CI: 1.09-2.42). Ayrıca kontrol grubunu CHG grubu ile karşılaştırdığımızda, CRE’de nega-tifleşme oranlarında anlamlı bir fark bulunmadı (p= 0.804). VRE’de iki grup arasında anlamlı fark saptandı (p= 0.048).Sonuç: Çocuk yoğun bakım ünitesinde gün aşırı %2 CHG ile cilt banyosu yapmanın VRE kolonizasyonunu önemli ölçüde azalttığını, ancak CRE kolonizasyonu riskini azaltmadığını göstermektedir. Çocuk yoğun bakım ünitesinde gün aşırı %2 CHG ile cilt banyosunun dirençli mikroorganizma kolonizasyonu ve infeksiyon önleme yöntemlerinden biri olarak kullanılabileceğini düşünmekteyiz.

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Cite This Article

SANDAL, Ö., YAŞAR, N., CEYLAN, G., ÇOLAK, M., BÖNCÜOĞLU, E., DEVRİM, İ., AYHAN, F. Y., AĞIN, H., TOPAL, S., ATAKUL, G., SOYDAN, E., KARAARSLAN, U. (2022). Does Skin Bathing With Chlorhexidine Gluconate (2%) Affect the Carbapenem-resistant Enterobacteriaceaeand Vancomycin-resistant Enterococcus Colonization in Pediatric Intensive Care?. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 26 - Sayı: 1, 189–195. https://ajindex.com/articles/517053

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