Journals / Çocuk Acil ve Yoğun Bakım Dergisi / 2017 / Cilt: 4 - Sayı: 2

Serratia Marcescens Septic Arthritis in a Case of Escobar Syndrome

Escobar Sendromlu Bir Olguda Serratia Marcescens Septik Artriti

Pages
84–88
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we present a rare case of septic arthritis caused by Serratia marrascens after a bacteremia in a patient with Escobar variant of Multiple Pterygium syndrome who had a central vascular access device and was hospitalized in the pediatric intensive care unit.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Septic arthritis is an inflammation of the synovial membrane and synovial fluid in the joints caused by bacterial, viral or fungal agents.
📊
Key Findings & Data:Since it has high morbidity rate, requires urgent intervention.
💡
Conclusion & Impact:Here, we present a rare case of septic arthritis caused by Serratia marrascens after a bacteremia in a patient with Escobar variant of Multiple Pterygium syndrome who had a central vascular access device and was hospitalized in the pediatric intensive care unit.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Septic arthritis is an inflammation of the synovial membrane and synovial fluid in the joints caused by bacterial, viral or fungal agents. Since it has high morbidity rate, requires urgent intervention. The synovial membrane is a highly vascular structure, but because it is not a protective basement membrane, the microorganisms that come through the bloodstream can easily settle here. For this reason, it should be kept in mind that an infection such as septic arthritis may develop in a hematogenous way in patients exposed to many invasive procedures, and having long-term catheter in pediatric intensive care unit. Serratia species are a gram-negative facultative anaerobic population of the Enterobacteriaceae group and have become more common in recent years as a cause of hospital-acquired bacteremia, pneumonia and urinary tract infections in intensive care units. However, primary joint infections secondary to infection with Serratia marcescens are extremely rare. Almost all cases were seen in trauma patients, immunocompromised patients, in those with central catheters and intensive care patients. When septic arthritis due to Serratia marcescens is not treated urgently, septicemia and mortality risk is high and may cause permanent destruction of the joint. Here, we present a rare case of septic arthritis caused by Serratia marrascens after a bacteremia in a patient with Escobar variant of Multiple Pterygium syndrome who had a central vascular access device and was hospitalized in the pediatric intensive care unit.

Özet

Septik artrit, yüksek morbidite ile seyreden ve acil girişim gerektiren eklemlerdeki sinovyal sıvı ve sinovyal zarın çeşitli etkenlerle oluşan enfeksiyonudur. Sinovyal zarın damarsal yapısından dolayı hematojen yolla gelen mikroorganizmalar kolaylıkla ekleme yerleşebilir. Bu nedenle çocuk yoğun bakımda uzun süre yatan kateteri olup birçok invazif girişime maruz kalan hastalarda septik artrit gibi bir enfeksiyonun hematojen yolla gelişebileceği akılda tutulmalıdır. Serratia türleri Enterobacteriaceae grubunun Gram-olumsuz fakültatif anaerobik basilleri olup özellikle son yıllarda yoğun bakım ünitelerinde hastane kökenli bakteriyemi, pnömoni ve idrar yolu enfeksiyonlarının bir nedeni olarak daha yaygın hale gelmiştir. Bununla birlikte, birincil eklem enfeksiyonları, Serratia marcescens'e ikincil olarak son derece nadirdir. Olguların hemen hemen tamamı travma hastalarında, bağışıklığı baskılanmış, santral kateteri olan ve yoğun bakımda izlenen hastalarda görülmüştür. Serratia marcescens'e bağlı septik artrit acilen tedavi edilmediğinde septisemi ve mortalite riski yüksek olup eklemde kalıcı destrüksiyona neden olabilir. Bu yazıda Multipl Pterigium sendromu olan Escobar sendromu nedeniyle çocuk yoğun bakımda izlenen ve santral kateteri olan bir olguda bakteriyemi sonrası gelişen Serratia marcescens septik artriti nadir bir durum olması nedeniyle sunulmuştur.

🔖

Cite This Article

SANDAL, Ö. S., SARI, F., CEYLAN, G., İŞGÜDER, R., DEVRİM, İ., AĞIN, H. (2017). Serratia Marcescens Septic Arthritis in a Case of Escobar Syndrome. Çocuk Acil ve Yoğun Bakım Dergisi, Cilt: 4 - Sayı: 2, 84–88. https://ajindex.com/articles/158535

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Calvo C, Nunez E, Camacho M, Clemente D, Fernández-Cooke E. Epidemiology and Management of Acute, Uncomplicated Septic Arthritis and Osteomyelitis. Spanish Multicenter Study. Pediatr Infect Dis J. 2016;35:1288-93
  2. Lampe RM. Osteomyelit and suppurative arthritis. In: Behrman R, Kliegman RM, I Jenson HB (eds). Nelson Textbook of Pediatrics. 17th ed. Philadelphia, Saunders. 2003;2297-302
  3. Cayce IV KO, Galloway MT. Infection In: Fischgrund JS (ed). Orthopaedic knowledge update 9. Rosemont, American Academy of Orthopaedic Surgeons; 2008:241-57
  4. Tachdjian MO. Bone and Joint Infections. In: Herring JA (ed). Tachdjian's pediatric orthopaedics. Philadelphia. Saunders WB; 2002:1841-77
  5. Kabak S, Halici M, Akcakus M, Cetin N, Narin N. Septic arthritis in patients followed- up in neonatal intensive care unit. Pediatr Int. 2002;44:652-7
  6. Bonhoeffer J, Haeberle B, Schaad UB, Heininger U. Diagnosis of acute haematogenous osteomyelitis and septic arthritis: 20 years experience at the University Children's Hospital Basel. Swiss Med Wkly. 2001;131:575-81
  7. Mathews CJ, Coakley G. Septic arthritis: current diagnostic and therapeutic algorithm. Curr Opin Rheumatol. 2008;20:457-62
  8. Mathews CJ, Kingsley G, Field M, Jones A, Weston VC, et al. Management of septic arthritis: a systematic review. Postgrad Med J. 2008;84:265-70
  9. Murillo O, Gomez-Junyent J, Grau I, Ribera A, Cabrera C, et al. Clinical findings of bacteremic septic arthritis according to the site of acquisition: The overlap between health care-related and community- and nosocomial-acquired cases. Eur J Intern Med. 2016;28:38-42
  10. Krogstad P. Septic arthritis. In: Cherry JD, Harrison GJ, Kaplan SL (eds). Feigin and Cherry's Textbook of Pediatric Infectious Diseases, 7th ed. Elsevier Saunders, Philadelphia; 2014:727
  11. Yamagishi Y, Togawa M, Shiomi M. Septic arthritis and acute hematogenous osteomyelitis in childhood at a tertiary hospital in Japan. Pediatr Int. 2009;51:371-6
  12. Fowler VG Jr, Justice A, Moore C, Benjamin DK Jr, Woods CW, et al. Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia. Clin Infect Dis. 2005;40:695-703
  13. Amao-Ruiz E, Correa-Fernandez AM, de la Fuente Galán L. Serratia marcescens septic sternoclavicular joint arthritis: A case report. Reumatol Clin. 2016;12:238-9
  14. Chiu LQ, Wang W. A case of unusual Gram-negative bacilli septic arthritis in an immunocompetent patient. Singapore Med J. 2013;54:164