Journals / Çocuk Acil ve Yoğun Bakım Dergisi / 2018 / Cilt: 5 - Sayı: 3

Angioedema and Urticaria Associated with Fluoxetine in a Preadolescent Boy

Preadolesan Bir Erkek Çocukta Fluoksetinle İlişkili Anjiyoödem ve Ürtiker

Pages
144–146
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We assume that our case is unique inthis respect for that angioedema developed with therapeutic dosesand thought to be allergic.

📌 3 Key Takeaways

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Objective & Hypothesis:Angioedema is defined as increased permeability and dilatation ofthe capillaries in the deep dermis or subcutaneous or submucosaltissues leading to localized swelling, often affecting the upperrespiratory and gastrointestinal tracts.
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Key Findings & Data:Here, we report a 10-year-oldboy who had urticaria with fluoxetine use, showed recovery aftercessation of the drug, and manifested with urticaria and angioedemaafter re-prescription.
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Conclusion & Impact:We assume that our case is unique inthis respect for that angioedema developed with therapeutic dosesand thought to be allergic.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Angioedema is defined as increased permeability and dilatation ofthe capillaries in the deep dermis or subcutaneous or submucosaltissues leading to localized swelling, often affecting the upperrespiratory and gastrointestinal tracts. It can also be observed asa rare adverse effect of selective serotonin reuptake inhibitors, asis the case with many other drugs. Here, we report a 10-year-oldboy who had urticaria with fluoxetine use, showed recovery aftercessation of the drug, and manifested with urticaria and angioedemaafter re-prescription. In the literature, there are two previous casereports of angioedema with fluoxetine. One case of angioedemaaccompanied by urticaria and showed a flu-like presentation 2 daysafter ingestion of high-dose fluoxetine. The other case, reportingangioedema with 10 mg/day, was without urticaria and thought tobe a pseudoallergic reaction. We assume that our case is unique inthis respect for that angioedema developed with therapeutic dosesand thought to be allergic.

Özet

Anjiyoödem, derin dermis veya deri altı dokulardaki kılcal damarların artmış geçirgenliği ve dilatasyonu ile seyreden ve sıklıkla üst solunum ve gastrointestinal sistemleri etkileyen lokal ödem olarak tanımlanır. Diğer birçok ilaç gibi, seçici serotonin geri alım inhibitörlerinin nadir bir yan etki olarak da görülebilir. Burada fluoksetin ile ürtikeri ortaya çıkan ve ilacın kesilmesinden sonra düzelen, ilacın tekrar başlanması ile ürtiker ve anjiyoödemi ortaya çıkan 10 yaşında bir erkek çocuğu sunuyoruz. Literatürde, fluoksetin ile ortaya çıkan 2 anjiyoödem olgusu daha bulunmaktadır. Birisi yüksek doz fluoksetin alımından 2 gün sonra grip benzeri bir klinik görünümle seyreden ve ürtiker ve anjiyoödemin eşlik ettiği olgu, diğeri ise 10 mg/gün fluoksetin ile anjiyoödem bildiren, ancak ürtiker görülmemesi nedeniyle psödoalerjik olduğu düşünülen olgudur. Bu açıdan bizim olgumuzun benzersiz olduğunu düşünüyoruz, çünkü anjiyoödem terapötik dozlarda gelişmiş ancak allerjik kökenli olarak değerlendirilmiştir.

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Cite This Article

BAŞARAN, A. E., ÖZATALAY, E., ÖNDER, A., SOĞUCAK, Z. E., ADANIR, A. S., BİNGÖL, A. (2022). Angioedema and Urticaria Associated with Fluoxetine in a Preadolescent Boy. Çocuk Acil ve Yoğun Bakım Dergisi, Cilt: 5 - Sayı: 3, 144–146. https://ajindex.com/articles/483824

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