Journals / Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi / 2010 / Cilt: 24 - Sayı: 2

Structure and function of glycoproteins

Glikoproteinlerin yapısı ve fonksiyonları

Pages
107–114
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The availability of glycoproteins in clinical treatments, and their significance in cancer were also highlighted.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Glycoproteins exist in various organisms varying from bacteria to human, and they have many described functions.
📊
Key Findings & Data:These proteins which have short oligosaccharides and serve in so many cellular events as cell surface recognition by hormones, viruses and other substances.
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Conclusion & Impact:The availability of glycoproteins in clinical treatments, and their significance in cancer were also highlighted.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Glycoproteins exist in various organisms varying from bacteria to human, and they have many described functions. These proteins which have short oligosaccharides and serve in so many cellular events as cell surface recognition by hormones, viruses and other substances. They also serve as cell surface antigens, outer cell matriks element, mucine secretion of gastrointestinale and urogenitale tracts. Furthermore, almost all globuler proteins in plasma, except albumin, secreted enzymes and proteins are show glycoprotein structure. In this review, we have given information about structure, function and the biological significance of the glycoproteins and the main methods used in the examination of glycoproteins. The availability of glycoproteins in clinical treatments, and their significance in cancer were also highlighted.

Özet

Glikoproteinler, bakteriden insana kadar pek çok canlıda bulunur ve farklı işlevlere sahiptir. Kısa oligosakkarit zincirlerine sahip bu proteinler pek çok hücresel olayda hormonlar, virüsler ve başka maddeler tarafından hücre yüzeyinin tanınmasında görev alırlar. Ayrıca hücre yüzey antijenleri, hücre dışı matriksin elemanı, gastrointestinal ve ürogenital yolun müsin salgısı olarak görev yaparlar. Bunların yanında albümin hariç plazmadaki globuler proteinlerin hemen hepsi, salgılanan enzimler ve proteinler glikoprotein yapısındadırlar. Bu derlemede glikoproteinlerin yapısı, fonksiyonları ve biyolojik önemi hakkında bilgi verilmiş, glikoproteinleri incelemede kullanılan yöntemlerden söz edilmiştir. Ayrıca, glikoproteinlerin klinik tedavide kullanılabilirliği ve kanserdeki önemi vurgulanmıştır.

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Cite This Article

UYSAL, H., AYPAK, S. Ü. (2022). Structure and function of glycoproteins. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi, Cilt: 24 - Sayı: 2, 107–114. https://ajindex.com/articles/515234

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