Journals / Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi / 2016 / Cilt: 30 - Sayı: 2

Effects of Coral and Demineralized Bone Matrix on Bone Healing

Koral ve Demineralize Kemik Matriksi'nin Kemik İyileşmesi Üzerine Olan Etkileri *

Pages
131–136
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was concluded that coral, DBM and coral plus DBM are effective on bone healing.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study was conducted to evaluate the accelerator effects of coral and demineralized bone matrix (DBM) on bone healing in rabbits.
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Key Findings & Data:Under the general anaesthesia, two bone defects models (3.5 mm diameter) were constituted on the proximal part of the tibia of all rabbits bilaterally.
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Conclusion & Impact:It was concluded that coral, DBM and coral plus DBM are effective on bone healing.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This study was conducted to evaluate the accelerator effects of coral and demineralized bone matrix (DBM) on bone healing in rabbits. Twelve male New Zealand white rabbits were divided into two equal groups. Under the general anaesthesia, two bone defects models (3.5 mm diameter) were constituted on the proximal part of the tibia of all rabbits bilaterally. Twelve bone defects were left empty (Control group). The other defects were filled with coral, DBM and coral plus DBM, respectively (twelve defects in each group). Clinical, radiographic and histologic examinations were performed after surgery on the 30th and 60th days. In radiological examinations, it was determined that the bone healing was better in coral, DBM and coral plus DBM groups than in the control group. Results of the histological examinations on the 30th and 60th day shown that bone healing was better in the grafted groups than the control group. It was concluded that coral, DBM and coral plus DBM are effective on bone healing.

Özet

Bu çalışma koral ve demineralize kemik matriksinin (DBM) tavşanlarda kemik iyileşmesi üzerindeki hızlandırıcı etkilerini değerlendirmek üzere yapılmıştır. On iki adet erkek Yeni Zelanda tavşanı iki eşit gruba ayrıldı. Genel anestezi altında bütün tavşanlarda bilateral olarak tibialarının proksimal bölümünde ikişer adet unikortikal kemik defektleri (3.5 mm çapında) oluşturuldu. On iki kemik defekti boş bırakıldı (Kontrol grubu). Diğer defektler (her bir grupta 12 adet defekt) sırasıyla koral, DBM ve koral+DBM ile dolduruldular. Klinik, radyografik ve histolojik muayeneler operasyon sonrasında, 30. ve 60. günlerde gerçekleştirildi. Radyolojik muayenelerde kemik iyileşmesinin koral, DBM ve koral+DBM gruplarında kontrol grubundan daha iyi olduğu belirlendi. Otuzuncu ve 60. günlerde yapılan histolojik muayenelerde kontrol grubuna göre kemik iyileşmesinin greft uygulanan gruplarda daha iyi olduğu belirlendi. Sonuç olarak koral, DBM ve koral+DBM uygulamalarının kemik iyileşmesinde olumlu etkilerinin bulunduğu kanısına varılmıştır.

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Cite This Article

DURMUŞ, A. S., ÇERİBAŞI, A. O., CAN, H. N. (2022). Effects of Coral and Demineralized Bone Matrix on Bone Healing. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi, Cilt: 30 - Sayı: 2, 131–136. https://ajindex.com/articles/515005

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