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Journals / Eurasian Journal of Medical Investigation / 2019 / Cilt: 3 - Sayı: 2

Hyperhomocysteinemi in Patients with Diverticula of the Colon

Omer EMECEN
Ahmet Cumhur DULGER
Selahattin VURAL
Arzu AYRALER
Raziye TURAN
Aysegul Torun GOKTAS
Mustafa YAKARİSİK
Pages
100–102
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

According to multiple logistic regression, HHcy developed more with aging and male gender was a strong risk factor for HHcy (all p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Hyperhomocysteinemia (HHcy) have been associated with cerebrovascular events, cardiac diseases and vascular thrombosis.
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Key Findings & Data:The aim of this study was to evaluate serum homocysteine levels in patients with DC.Methods: We consecutively evaluated 115 patients (65 male, mean age 65±12.1 years) with DC.
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Conclusion & Impact:According to multiple logistic regression, HHcy developed more with aging and male gender was a strong risk factor for HHcy (all p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Hyperhomocysteinemia (HHcy) have been associated with cerebrovascular events, cardiac diseases and vascular thrombosis. HHcy is caused by cyanocobalamin and folate deficiencies. Diverticula of the colon (DC) is caused by herniation of the colonic mucosa and submucosa. The aim of this study was to evaluate serum homocysteine levels in patients with DC.Methods: We consecutively evaluated 115 patients (65 male, mean age 65±12.1 years) with DC. Baseline serum levels of homocystein, folate and vitamin B12 were retrospectively obtained from hospital data. Plasma homocystein was measured by high performance liquid chromatography with a fluorescence detector. Diagnosis of DC was done by colonoscopy. The chi-squared test and independentt test were used for comparison.Results: DC patients had significantly higher levels of homocysteine compared with normal levels (16.4±11.2 μg/l; normal ranges 0-12 μg/l). Otherhand, mean vitamin B12 level was 470±317mg/dl and theme an folate level was 9.3±4.3 mg/dl. According to multiple logistic regression, HHcy developed more with aging and male gender was a strong risk factor for HHcy (all p

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Cite This Article

EMECEN, O., DULGER, A. C., VURAL, S., AYRALER, A., TURAN, R., GOKTAS, A. T., YAKARİSİK, M. (2022). Hyperhomocysteinemi in Patients with Diverticula of the Colon. Eurasian Journal of Medical Investigation, Cilt: 3 - Sayı: 2, 100–102. https://ajindex.com/articles/508728

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