Dergiler / Eurasian Journal of Medical Investigation / 2019 / Cilt: 3 - Sayı: 2

Hyperhomocysteinemi in Patients with Diverticula of the Colon

Sayfa
100–102
Yayın Tarihi
2022-10-12
DOI
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According to multiple logistic regression, HHcy developed more with aging and male gender was a strong risk factor for HHcy (all p

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: Hyperhomocysteinemia (HHcy) have been associated with cerebrovascular events, cardiac diseases and vascular thrombosis.
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Temel Bulgular & Veri:The aim of this study was to evaluate serum homocysteine levels in patients with DC.Methods: We consecutively evaluated 115 patients (65 male, mean age 65±12.1 years) with DC.
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Sonuç & Katkı:According to multiple logistic regression, HHcy developed more with aging and male gender was a strong risk factor for HHcy (all p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objectives: Hyperhomocysteinemia (HHcy) have been associated with cerebrovascular events, cardiac diseases and vascular thrombosis. HHcy is caused by cyanocobalamin and folate deficiencies. Diverticula of the colon (DC) is caused by herniation of the colonic mucosa and submucosa. The aim of this study was to evaluate serum homocysteine levels in patients with DC.Methods: We consecutively evaluated 115 patients (65 male, mean age 65±12.1 years) with DC. Baseline serum levels of homocystein, folate and vitamin B12 were retrospectively obtained from hospital data. Plasma homocystein was measured by high performance liquid chromatography with a fluorescence detector. Diagnosis of DC was done by colonoscopy. The chi-squared test and independentt test were used for comparison.Results: DC patients had significantly higher levels of homocysteine compared with normal levels (16.4±11.2 μg/l; normal ranges 0-12 μg/l). Otherhand, mean vitamin B12 level was 470±317mg/dl and theme an folate level was 9.3±4.3 mg/dl. According to multiple logistic regression, HHcy developed more with aging and male gender was a strong risk factor for HHcy (all p

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Bu Makaleye Atıf Yap

EMECEN, O., DULGER, A. C., VURAL, S., AYRALER, A., TURAN, R., GOKTAS, A. T., YAKARİSİK, M. (2022). Hyperhomocysteinemi in Patients with Diverticula of the Colon. Eurasian Journal of Medical Investigation, Cilt: 3 - Sayı: 2, 100–102. https://ajindex.com/articles/508728

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Kaynakça (12)

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