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Journals / Epilepsi / 2018 / Cilt: 24 - Sayı: 3

Seizure Induced by Extended-Release Bupropion Used for Smoking Cessation at Early Term and Therapeutic Dose

Sigara Bırakmada Kullanılan Yavaş Salınımlı Bupropionun Erken Dönem ve Terapötik Dozda Neden Olduğu Nöbet

Aslı AKSOY GÜNDOĞDU
Zeynep ÖZÖZEN AYAS
Journal
Epilepsi
Pages
127–129
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We also emphasized that extended-release bupropion, whichis commonly used for smoking cessation therapy, may cause seizure at early term and therapeutic dose.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Bupropion inhibits reuptakes of dopamine and noradrenaline.
📊
Key Findings & Data:In the present article, we report a case of a 30-year-old man presentingwith generalized tonic clonic seizures induced by extended-release bupropion.
💡
Conclusion & Impact:We also emphasized that extended-release bupropion, whichis commonly used for smoking cessation therapy, may cause seizure at early term and therapeutic dose.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Bupropion inhibits reuptakes of dopamine and noradrenaline. Since it is also a nicotine receptor antagonist, it acts as a drug used for smokingcessation. Bupropion is commonly preferred because of no side effects on weight, sexual function, and the lack of sedative effect. Immediateand sustained-release bupropion forms may trigger seizure activity. In the present article, we report a case of a 30-year-old man presentingwith generalized tonic clonic seizures induced by extended-release bupropion. We also emphasized that extended-release bupropion, whichis commonly used for smoking cessation therapy, may cause seizure at early term and therapeutic dose.

Özet

Bupropion, dopamin ve noradrenalin geri alımlarını inhibe etmektedir. Aynı zamanda bir nikotin reseptör antagonisti olduğu için sigara bırakma için kullanılan bir ilaç olarak işlev görür. Bupropion kilo, cinsel fonksiyon üzerine yan etkisi olmaması ve sedatif etkisi olmamasından dolayı yaygın olarak tercih edilmektedir. Hızlı ve sürekli salınan bupropion formları nöbet aktivitesini tetikleyebilir. Bu yazıda, 30 yaşında erkek hastada yavaş salınımlı bupropiyonun neden olduğu jeneralize tonik klonik nöbet sunulmaktadır. Ayrıca sigarayı bırakma tedavisinde yaygın olarak kullanılan yavaş salınan bupropiyonun erken dönemde ve terapötik dozda nöbete neden olabileceğini vurguladık.

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Cite This Article

GÜNDOĞDU, A. A., AYAS, Z. Ö. (2022). Seizure Induced by Extended-Release Bupropion Used for Smoking Cessation at Early Term and Therapeutic Dose. Epilepsi, Cilt: 24 - Sayı: 3, 127–129. https://ajindex.com/articles/501662

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