Journals / Epilepsi / 2020 / Cilt: 26 - Sayı: 3

Evaluation of Obstructive Sleep Apnea Syndrome in Epilepsy Patients with Polysomnographic Data

Epilepsi Hastalarında Polisomnografik Verilerle Obstrüktif Uyku Apne Sendromunun Değerlendirilmesi

Journal
Epilepsi
Pages
193–197
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Clinical screening of OSAS in settings of epileptic patients may be needed to diagnose to find out it maybe a potential and modifiable risk factor for epilepsy.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Sleep respiratory disorders, which are more common in epilepsy patients, are treatable diseases.
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Key Findings & Data:Methods: For this study, from 1120 patients with epilepsy, 32 of them who were diagnosed with OSA in the PSG test were selected.
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Conclusion & Impact:Clinical screening of OSAS in settings of epileptic patients may be needed to diagnose to find out it maybe a potential and modifiable risk factor for epilepsy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Sleep respiratory disorders, which are more common in epilepsy patients, are treatable diseases. We have discussed the diagnosis of sleep apnea syndrome after PSG of epileptic patients with visible apnea and snoring, in light of the findings in the literature. Methods: For this study, from 1120 patients with epilepsy, 32 of them who were diagnosed with OSA in the PSG test were selected. Thirty-two patients with epilepsy that snoring and apnea who consulted sleep center. Patients with simple snoring and upper airway resistance were not selected. Epworth Sleep Scales was applied to all patients and all patients were taken. Results: In this study, the findings showed that the ratio of OUAS in patients with epilepsy was 2.9%. 21 of the 32 cases were male and 11 were female. The mean age was 53 (42–69) years. 72% had partial epilepsies and 28% generalized. The Apne-hypopnea index was 28 (14–48). PAP treatment was performed after the diagnosis of sleep apnea syndrome. Conclusion: Sleep respiratory disorders are more common in patients with epilepsy than the rest of the population and they are treatable diseases. The other study revealed that the frequency of OSAS among epilepsy was10,2%. In this study, the findings showed that the ratio of OSAS in patients with epilepsy was 2.9%.This a risk for OSAS and the medication used for the treatment should be selected appropriately. Clinical screening of OSAS in settings of epileptic patients may be needed to diagnose to find out it maybe a potential and modifiable risk factor for epilepsy.

Özet

Amaç: Uykudaki solunum bozuklukları, normal popülasyona göre epilepsi hastalarında daha sık görülen, tedavi edilebilir hastalıklardır. Bu çalışmamızda, belirgin apne ve horlaması olan epileptik hastaların Obstrüktif Uyku Apne Sendromu (OUAS) varlığı polisomnografi (PSG) verileri eşliğinde değerlendirilmiş olup literatür bulguları ile birlikte tartışılmıştır. Gereç ve Yöntem: Bu çalışmamızda, 1120 epilepsi hastasından, uyku merkezine horlama ve apne nedeniyle PSG testi uygulanarak OUAS tanısı alan 32 hasta seçildi. Basit horlama ve üst solunum yolu rezistansı olan hastalar çalışmaya dahil edilmedi. Tüm hastalara Epworth Uyku Ölçeği uygulandı. Bulgular: Epilepsili hastalarında OUAS oranının %2.9 olduğu saptadı. Olguların 21’i erkek, 11’i kadındı. Ortalama yaş 53 (42–69) idi. %72’sinde fokalepilepsi ve %28’inde jeneralize epilepsi vardı. Apne-hipopne indeksi 28 (14–48) idi. Uyku apne sendromu tanısı konulduktan sonra tüm hastalara pozitif havayolu basıncı tedavisi uygulandı. Sonuç: Uykuda solunum bozuklukları epilepsili hastalarda normal popülasyondan daha yaygındır ve tedavi edilebilir hastalıklardır. Bir çalışmada, epilepsi arasındaOUAS sıklığının %10.2 olduğunu ortaya konulmuştur. Bu çalışmada epilepsili hastalarında OUAS oranının %2.9 olduğu saptanmıştır. Epilepsi için potansiyel ve değiştirilebilir bir risk faktörü olan OUAS varlığını teşhis etmek için epileptik hastalarda klinik değerlendirme gerekebilir.

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Cite This Article

DEMİR, A. B., BORA, İ., LEBA, L. K. (2022). Evaluation of Obstructive Sleep Apnea Syndrome in Epilepsy Patients with Polysomnographic Data. Epilepsi, Cilt: 26 - Sayı: 3, 193–197. https://ajindex.com/articles/501636

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References (16)

  1. Sander JW. The epidemiology of epilepsy revisited. Curr Opin Neurol 2003;16(2):165–70
  2. Touchon J, Baldy-Moulinier M, Billiard M, Besset A, Cadilhac J. Sleep organization and epilepsy. Epilepsy Res Suppl 1991;2:73– 81
  3. Derry CP, Duncan S. Sleep and epilepsy. Epilepsy Behav 2013;26(3):394–404
  4. Malow BA, Fromes GA, Aldrich MS. Usefulness of polysomnography in epilepsy patients. Neurology 1997;48(5):1389–94
  5. Manni R, Terzaghi M, Arbasino C, Sartori I, Galimberti CA, Tartara A. Obstructive sleep apnea in a clinical series of adult epilepsy patients: frequency and features of the comorbidity. Epilepsia 2003;44(6):836–40
  6. Tomfohr LM, Ancoli-Israel S, Loredo JS, Dimsdale JE. Effects of continuous positive airway pressure on fatigue and sleepiness in patients with obstructive sleep apnea: data from a randomized controlled trial. Sleep 2011;34(1):121–6
  7. Muller JE, Tofler GH, Stone PH. Circadian variation and triggers of onset of acute cardiovascular disease. Circulation 1989;79(4):733–43
  8. Köktürk O. Uykuda solunum bozuklukları. Tarihçe, tanımlar, hastalık spektrumu ve boyutu. Tüberküloz ve Toraks Dergisi 1998;46:187–92
  9. Vaughn BV, D’Cruz OF. Sleep and epilepsy. Semin Neurol 2004;24(3):301–13. 10. van Golde EG, Gutter T, de Weerd AW. Sleep disturbances in people with epilepsy; prevalence, impact and treatment. Sleep Med Rev 2011;15(6):357–68
  10. Schwab RJ, Goldberg AN, Pack AI. Sleep apnea syndromes. In: Fishman AP, editor. Fishman’s Pulmonary Diseases and Disorders. NewYork: McGraw-Hill Book Company; 1998. p. 1617–37
  11. Malow BA, Foldvary-Schaefer N, Vaughn BV, Selwa LM, Chervin RD, Weatherwax KJ, et al. Treating obstructive sleep apnea in adults with epilepsy: a randomized pilot trial. Neurology 2008;71(8):572–7
  12. Nashef L, Ryvlin P. Sudden unexpected death in epilepsy (SUDEP): update and reflections. Neurol Clin 2009;27(4):1063–74
  13. Oliveira AJ, Zamagni M, Dolso P, Bassetti MA, Gigli GL. Respiratory disorders during sleep in patients with epilepsy: effect of ventilatory therapy on EEG interictal epileptiform discharges. Clin Neurophysiol 2000;111 Suppl 2:S141–5
  14. Holmes MD, Chang M, Kapur V. Sleep apnea and excessive daytime somnolence induced by vagal nerve stimulation. Neurology 2003;61(8):1126–9
  15. Smith PL, Gold AR, Meyers DA, Haponik EF, Bleecker ER. Weight loss in mildly to moderately obese patients with obstructive sleep apnea. Ann Intern Med 1985;103(6):850–5
  16. Guilleminault C. Clinical features and evaluation of