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Journals / Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.) / 2013 / Cilt: 24 - Sayı: 3

Okronoziste total diz artroplastisi: Olgu sunumu ve kritik literatür incelemesi

Total knee arthroplasty in ochronosis: A case report and critical review of the literature

Ramadan ÖZMANEVRA
Ortaç GÜRAN
Vasfi KARATOSUN
İzge GÜNAL
Pages
169–172
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A critical review of the literaturerevealed no uniformity in reporting such cases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Alkaptonuria is an autosomal recessive disorder caused bythe deficiency of homogentisate 1.2 dioxygenase activity.The clinical presentation shows an ochronotic pigmentwhich is deposited in all connective tissues, including incartilage, particularly.
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Key Findings & Data:In this article, we present a69-year-old male case who underwent bilateral cemented totalknee arthroplasty simultaneously.
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Conclusion & Impact:A critical review of the literaturerevealed no uniformity in reporting such cases.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Alkaptonuria is an autosomal recessive disorder caused bythe deficiency of homogentisate 1.2 dioxygenase activity.The clinical presentation shows an ochronotic pigmentwhich is deposited in all connective tissues, including incartilage, particularly. The knee is the most common siteof peripheral abnormality. There is currently no definitivecure for alkaptonuric ochronosis. In this article, we present a69-year-old male case who underwent bilateral cemented totalknee arthroplasty simultaneously. Our results during two-yearfollow-up were satisfactory. A critical review of the literaturerevealed no uniformity in reporting such cases.

Özet

Alkaptonüri, homogentisat 1.2 dioksigenaz enzimi aktivitesindeki eksikliğe bağlı gelişen otozomal resesif geçişli birhastalıktır. Klinik tabloda kıkırdak başta olmak üzere tüm bağ dokusunda biriken okronotik pigment birikimi görülür.Periferik anormalliğin en sık görüldüğü yer diz eklemidir. Günümüzde alkaptonürik okronozisin kesin bir tedavisi yoktur. Bu yazıda, aynı seansta iki taraflı çimentolu total dizartroplastisi uygulanan 69 yaşında bir erkek olgu sunuldu. İki yıllık takip sonuçları tatmin ediciydi. Kritik literatür incelemesinde bu tür olgularda standart bir yaklaşıma rastlanmadı.

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Cite This Article

ÖZMANEVRA, R., GÜRAN, O., KARATOSUN, V., GÜNAL, İ. (2022). Okronoziste total diz artroplastisi: Olgu sunumu ve kritik literatür incelemesi. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.), Cilt: 24 - Sayı: 3, 169–172. https://ajindex.com/articles/498639

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References (15)

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