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Journals / Ege Klinikleri Tıp Dergisi / 2022 / Cilt: 60 - Sayı: 1

Is Glycated Hemoglobin Lower in SARS CoV 2 Patients with Diabetes Mellitus?

Diyabetik SARS CoV 2 Hastalarında Glikolize Hemoglobin Daha Düşük mü Saptanıyor?

Yusuf ÜZÜM
Zeynep Zehra GÜMÜŞ
Orhan BALIKCI
Uğur Bayram KORKMAZ
Süleyman GÜNAY
Pages
69–74
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

For this reason, it would be inappropriate to make a clinical decision by only evaluating HbA1c values during the regulation of blood glucose levels in COVID-19 patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives To compare the glycemic status of diabetic patients before and during COVID 19 and to evaluate the accuracy of HbA 1 c levels Material and Methods Confirmed 25 adult COVID 19 diabetic patients hospitalized between March 2020 and July 2020 were included in the present analysis Medical records of the included patients were retrospectively reviewed HbA 1 c and hemoglobin levels in the last 6 months and at the hospital admission were recorded and compared According to measured HbA 1 c at hospital admission, estimated average glucose eAG was calculated by Nathan regression equation formula and compared the measured average blood glucose ( Also, documented HbA 1 c called previous HbA 1 c (p HbA 1 c) and hemoglobin called previous hemoglobin (p Hemoglobin) levels in the last 6 months was compared with the level of HbA 1 c and Hemoglobin in hospital admission Results The AG values 176 44 mg/dl) were found higher than eAG values 151 34 mg/dl) but did not show any statistical difference ( 0 250 Previous HbA 1 c values were significantly higher than current HbA 1 c 8 08 and 6 80 respectively and p= 0 020 Conclusion: HbA1c values may be lower than they should be in diabetic COVID-19 patients and these results may not accurately reflect the patient's glycemic status.
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Key Findings & Data:Objectives To compare the glycemic status of diabetic patients before and during COVID 19 and to evaluate the accuracy of HbA 1 c levels Material and Methods Confirmed 25 adult COVID 19 diabetic patients hospitalized between March 2020 and July 2020 were included in the present analysis Medical records of the included patients were retrospectively reviewed HbA 1 c and hemoglobin levels in the last 6 months and at the hospital admission were recorded and compared According to measured HbA 1 c at hospital admission, estimated average glucose eAG was calculated by Nathan regression equation formula and compared the measured average blood glucose ( Also, documented HbA 1 c called previous HbA 1 c (p HbA 1 c) and hemoglobin called previous hemoglobin (p Hemoglobin) levels in the last 6 months was compared with the level of HbA 1 c and Hemoglobin in hospital admission Results The AG values 176 44 mg/dl) were found higher than eAG values 151 34 mg/dl) but did not show any statistical difference ( 0 250 Previous HbA 1 c values were significantly higher than current HbA 1 c 8 08 and 6 80 respectively and p= 0 020 Conclusion: HbA1c values may be lower than they should be in diabetic COVID-19 patients and these results may not accurately reflect the patient's glycemic status.
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Conclusion & Impact:For this reason, it would be inappropriate to make a clinical decision by only evaluating HbA1c values during the regulation of blood glucose levels in COVID-19 patients.
🔬Design:Review & Systematic Survey
📍Scope:2020 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives To compare the glycemic status of diabetic patients before and during COVID 19 and to evaluate the accuracy of HbA 1 c levels Material and Methods Confirmed 25 adult COVID 19 diabetic patients hospitalized between March 2020 and July 2020 were included in the present analysis Medical records of the included patients were retrospectively reviewed HbA 1 c and hemoglobin levels in the last 6 months and at the hospital admission were recorded and compared According to measured HbA 1 c at hospital admission, estimated average glucose eAG was calculated by Nathan regression equation formula and compared the measured average blood glucose ( Also, documented HbA 1 c called previous HbA 1 c (p HbA 1 c) and hemoglobin called previous hemoglobin (p Hemoglobin) levels in the last 6 months was compared with the level of HbA 1 c and Hemoglobin in hospital admission Results The AG values 176 44 mg/dl) were found higher than eAG values 151 34 mg/dl) but did not show any statistical difference ( 0 250 Previous HbA 1 c values were significantly higher than current HbA 1 c 8 08 and 6 80 respectively and p= 0 020 Conclusion: HbA1c values may be lower than they should be in diabetic COVID-19 patients and these results may not accurately reflect the patient's glycemic status. For this reason, it would be inappropriate to make a clinical decision by only evaluating HbA1c values during the regulation of blood glucose levels in COVID-19 patients.

Özet

Amaç Diyabetik hastaların COVID 19 enfeksiyonu öncesi ve enfeksiyon sırasındaki glisemik durumlarını karşılaştırmak ve HbA 1 c Glikolize hemoglobin) düzeylerinin doğruluğunu değerlendirmek Gereç ve Yöntemler Mart 2020 ile Temmuz 2020 arasında hastaneye yatırılan COVID 19 olduğu PCR testi ile doğrulanmış 25 yetişkin diyabetik COVID 19 hastası çalışmaya dahil edildi Dahil edilen hastaların tıbbi kayıtları geriye dönük olarak incelendi Son 6 aydaki ve hastaneye yatıştaki HbA 1 c ve hemoglobin düzeyleri kaydedildi ve karşılaştırıldı Hastaneye kabulde ölçülen HbA 1 c'ye göre, tahmini ortalama glikoz eAG seviyesi, Nathan regresyon denklem formülü ile hesaplandı ve ölçülen ortalama kan şekeri ile ( karşılaştırıldı Ayrıca son 6 ayda bakılan HbA 1 c önceki HbA 1 c (p HbA 1 c) olarak ve önceki hemoglobin değeri ise hemoglobin (p Hemoglobin) olarak kaydedildi, bunların düzeyleri hastaneye yatıştaki HbA 1 c ve Hemoglobin düzeyleri ile karşılaştırıldı Bulgular AG değerleri 176 44 mg/dl), eAG değerlerinden 151 34 mg/dl) daha yüksek bulundu ancak istatistiksel bir farklılık göstermedi ( 0 250 Önceki HbA 1 c değerlerinin ortalaması mevcut HbA 1 c değerlerinin ortalamasından anlamlı derecede yüksekti (sırasıyla 8 08 ve 6 80 ve p= 0 020 Sonuç Diyabetik COVID 19 hastalarında HbA 1 c değerleri olması gerekenden düşük olabilir ve bu sonuçlar hastanın glisemik durumunu doğru yansıtmayabilir Bu nedenle COVID 19 hastalarında kan şekeri düzeylerinin düzenlenmesi sırasında sadece HbA 1 c değerlerini değerlendirerek klinik bir karar vermek uygun olmayabilir

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Cite This Article

ÜZÜM, Y., GÜMÜŞ, Z. Z., BALIKCI, O., KORKMAZ, U. B., GÜNAY, S. (2022). Is Glycated Hemoglobin Lower in SARS CoV 2 Patients with Diabetes Mellitus?. Ege Klinikleri Tıp Dergisi, Cilt: 60 - Sayı: 1, 69–74. https://ajindex.com/articles/495558

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