Journals / Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2018 / Cilt: 8 - Sayı: 1

An Overview of Etiopathogenesis of Acne Vulgaris

Akne Vulgaris Etiyopatogenezine Genel Bakış

Pages
44–51
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article, the epidemiology and etiopathogenesis of acne are overviewed.

📌 3 Key Takeaways

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Objective & Hypothesis:Acne vulgaris is a chronic inflammatory disease that primarily affects the pilosebase unit.
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Key Findings & Data:Acne vulgaris remains one of the commonest diseases to afflict humanity, with prevalence up to 90% during adolescence.
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Conclusion & Impact:In this article, the epidemiology and etiopathogenesis of acne are overviewed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Acne vulgaris is a chronic inflammatory disease that primarily affects the pilosebase unit. Acne vulgaris remains one of the commonest diseases to afflict humanity, with prevalence up to 90% during adolescence. Relatively little is known about its epidemiology despite the fact that acne is a universal condition in younger population. This disease is more common in developed countries than in less industrialized regions of the world. The etiopathogenesis of acne is multifactorial. Sebum production, follicular epithelial keratinization, bacterial proliferation, and inflammation play significant role in etiopathogenesis. Recent studies shown that toll like receptors and antimicrobial peptides play a role in the pathogenesis of acne vulgaris. The relationship between diet and acne is highly controversial. Strong evidence shows that high glycemic loads diet may exacerbate acne. In addition, the factors contributing to the formation of acne also include genetic predispositions, hormonal abnormalities, psychological, environmental and iatrogenic factors. The disease is mainly observed face, chest, back and shoulders. When acne is untreated, it may cause social isolation, difficulty in finding jobs, depression and suicide attempt as a result of emotional and physical scar formation. In this article, the epidemiology and etiopathogenesis of acne are overviewed.

Özet

Akne vulgaris başlıca pilosebase üniteyi etkileyen kronik inflamatuvar bir hastalıktır. Akne vulgaris adolesanlarda %90'avaran prevalansıyla, insanlığı etkileyen en sık görülen hastalıklardan biridir. Hastalığın epidemiyolojisi ile ilgili bilinenlernispeten az olmasına karşın; akne genç popülasyonda görülen evrensel bir durumdur. Bu hastalık gelişmiş ülkelerdedünyanın daha az endüstrileşmiş bölgelerinden daha yaygındır. Aknenin etiyopatogenezi multifaktöriyeldir.Etiyopatogenezinde sebum üretimi, foliküler epitelyal keratinizasyon, bakteriyel proliferasyon ve inflamasyon önemli roloynar. Güncel çalışmalar akne vulgaris etiyopatogenezinde toll benzeri reseptörler ve antimikrobiyal peptidlerin de roloynadığını göstermektedir. Akne ve diyet arasındaki ilişki ise son derece tartışmalıdır. Yüksek glisemik indeksli gıdalarınakne vulgarisi şiddetlendirdiğine yönelik güçlü kanıtlar mevcuttur. Ayrıca genetik yatkınlık, hormonal bozukluklar,psikolojik, çevresel ve iyatrojenik faktörler de akne gelişimine katkıda bulunur. Hastalık sıklıkla yüz, sırt, göğüs ve omuzbölgesini tutar. Tedavi edilmediği zaman emosyonel ve fiziksel bozukluklara neden olarak sosyal izolasyon, iş bulmagüçlüğü, depresyon ve intihar girişimine yol açabilmektedir. Bu makalede akne vulgarisin epidemiyolojisi veetiyopatogenezi gözden geçirilmiştir.

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Cite This Article

BAYKAN, A., ERTAŞ, R., ÖZLÜ, E. (2022). An Overview of Etiopathogenesis of Acne Vulgaris. Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Cilt: 8 - Sayı: 1, 44–51. https://ajindex.com/articles/494787

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