Journals / Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2021 / Cilt: 11 - Sayı: 3

Evaluation of Bone and Joint Involvement in Patients Followed with the Diagnosis of Brucellosis

Bruselloz tanısıyla Takip Edilen Hastalarda Kemik ve Eklem Tutulumunun Değerlendirilmesi

Pages
279–283
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Symptom duration, acute phase reactants, agglutination titer may be guiding for this.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Brucellosis is an important problem all over the world.
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Key Findings & Data:In thisstudy, we planned to reveal our experiences by examining the epidemiological, clinical, laboratory and radiologicalfeatures of brucellosis cases with and without bone-joint involvement.Material and Methods: This retrospective clinical study includes the data of 443 patients who were followed up withthe diagnosis of brucellosis between December 2014 and August 2019.
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Conclusion & Impact:Symptom duration, acute phase reactants, agglutination titer may be guiding for this.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Brucellosis is an important problem all over the world. The most common form is bone-joint involvement. In thisstudy, we planned to reveal our experiences by examining the epidemiological, clinical, laboratory and radiologicalfeatures of brucellosis cases with and without bone-joint involvement.Material and Methods: This retrospective clinical study includes the data of 443 patients who were followed up withthe diagnosis of brucellosis between December 2014 and August 2019. The epidemiological, clinical, laboratory andradiological findings of the patients were obtained from the patient files and hospital database. Patients were dividedinto two groups as with and without bone-joint involvement and their data were compared statistically.Results: A total of 443 patients who were followed up with a diagnosis of brucellosis were included in the study. 92(20.8%) of these patients had bone-joint involvement of brucellosis (sacroileitis, spondylodiscitis, arthritis, bursitis,synovitis). Magnetic resonance imaging method was used for diagnosis in patients with bone-joint involvement.Patients with bone-joint involvement had longer duration of complaints, and acute phase reactants and agglutinationtiters were higher.Conclusion: Bone-joint involvement in brucellosis is very important as it may cause inadequate treatment and may endwith sequelae. Radiological imaging is important in the diagnosis of bone-joint involvement, but unnecessary requestsshould also be avoided. Symptom duration, acute phase reactants, agglutination titer may be guiding for this.

Özet

Amaç: Bruselloz tüm dünyada hala önemli bir halk sağlığı sorunudur. En fazla görülen formu kemik-eklem tutulumudur. Biz bu çalışmada kemik-eklem tutulumu olan ve olmayan bruselloz olgularının epidemiyolojik, klinik, laboratuar ve radyolojik özelliklerini irdeleyip tecrübelerimizi ortaya koymayı planladık. Gereç ve Yöntemler: Bu retrospektif klinik çalışma, Aralık 2014-Ağustos 2019 tarihleri arasında bruselloz tanısıyla takip edilen toplam 443 hastanın verisini içermektedir. Hastaların epidemiyolojik, klinik, laboratuar ve radyolojik bulguları hasta dosyalarından ve hastane veri tabanından elde edilmiştir. Hastalar kemik-eklem tutulumu olan ve olmayan olarak iki ayrı gruba ayrılıp verileri istatistiksel olarak karşılaştırıldı. Bulgular: Çalışmaya bruselloz tanısıyla takip edilen toplam 443 hasta dahil edildi. Bu hastaların 92 (%20,8)’si bruselloza ait kemik-eklem (sakroileit, spondilodiskit, artrit, bursit, sinovit) tutulumuna sahipti. Kemik-eklem tutulumu olan hastaların tümünde tanı da manyetik rezonans görüntüleme yöntemi kullanılmıştı. Kemik-eklem tutulumu olan vakalarda şikayet süresi daha uzun, akut faz reaktanları ve aglütinasyon titresi daha yüksekti. Sonuç: Brusellozda kemik-eklem tutulumu hem tedavi yetersizliğine neden olabileceğinden hem de sekelle sonlanabileceğinden oldukça önemlidir. Kemik ve eklem tutulumunun tanısında radyolojik görüntülemenin önemi büyüktür fakat gereksiz istemlerden de kaçınılmalıdır. Bunun için semptom süresi, akut faz reaktanları, aglütinasyon titresi yol gösterici olabilir.

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Cite This Article

KAYA, S., KAVAK, Ş. (2022). Evaluation of Bone and Joint Involvement in Patients Followed with the Diagnosis of Brucellosis. Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Cilt: 11 - Sayı: 3, 279–283. https://ajindex.com/articles/494703

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References (16)

  1. Pappas G, Akritidis N, Bosilkovski M, Tsianos E. Brucellosis. N Engl J Med. 2005; 352(22): 2325
  2. Pappas G, Papadimitriou P, Akritidis N, Christou L, Tsianos EV. The new global map of human brucellosis. Lancet Infect Dis. 2006; 6(2): 91
  3. Jennings GJ, Hajjeh RA, Girgis FY, Fadeel MA, Maksoud MA, Wasfy MO, et al. Brucellosis as a cause of acute febrile illness in Egypt. Trans R Soc Trop Med Hyg. 2007; 101(7): 707
  4. Dean AS, Crump L, Greter H, Schelling E, Zinsstag J. Global burden of human brucellosis: A systematic review of disease frequency. PLoS Negl Trop Dis. 2012; 6(10): e1865
  5. Bosilkovski M, Krteva L, Caparoska S, Dimzova M. Osteoarticular involvement in brucellosis: study of 196 cases in the Republic of Macedonia. Croat Med J. 2004; 45(6): 727-33
  6. Geyik MF, Gür A, Nas K, Cevik R, Saraç J, Dikici B, et al. Musculoskeletal involvement of brucellosis in different age groups: a study of 195 cases. Swiss Med Wkly. 2002; 132(7-8): 98
  7. Esmaeilnejad-Ganji SM, Esmaeilnejad-Ganji SMR. Osteoarticular manifestations of human brucellosis: A review. World J Orthop. 2019; 10(2): 54
  8. Hashemi SH, Keramat F, Ranjbar M, Mamani M, Farzam A, Jamal-Omidi S. Osteoarticular complications of brucellosis in Hamedan, an endemic area in the west of Iran. Int J Infect Dis. 2007; 11(6): 496
  9. Colmenero JD, Ruiz-Mesa JD, Plata A, Bermúdez P, Martin-Rico P, Queipo-Ortuno MI, et al. Clinical findings, therapeutic approach, and outcome of brucellar vertebral osteomyelitis. Clin Infect Dis. 2008; 46(3): 426
  10. Mousa AM, Bahar RH, Araj GF, Koshy TS, Muhtaseb SA, al-Mudallal DS, et al. Neurological complications of brucella spondylitis. Acta Neurol Scand. 1990; 81(1): 16
  11. Solera J, Lozano E, Martinez-Alfaro E, Espinosa A, Castillejos ML, Abad L. Brucellar spondylitis: review of 35 cases and literature survey. Clin Infect Dis. 1999; 29(6): 1440
  12. Slack MPE. Gram negative coccobacilli. In: Armstrong D, Cohen J, eds. Infectious Disease. London: Harcourt Publishers, 1999: 8.20.1- 8.20.18. 7
  13. Tasova Y, Saltoğlu N, Yılmaz G, Inal S. Brucellosis: Evaluation of clinical, laboratory and treatment characteristics of 238 adult patients. Turk J Infect. 1998; 12: 307-12
  14. Franco MP, Mulder M, Gilman RH, Smits HL. Human brucellosis. Lancet Infect Dis. 2007; 7(12): 775-86
  15. Gotuzzo E, Seas C, Guerra JG, Carrillo C, Bocanegra TS, Calvo A, et al. Brucellar arthritis: a study of 39 Peruvian families. Ann Rheum Dis. 1987; 46(7): 506-9
  16. Al-Shahed MS, Sharif HS,