SavedAdd your journal

Journals / Arşiv Kaynak Tarama Dergisi / 2015 / Cilt: 24 - Sayı: 1

Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections: Role of Otolaryngologist

Streptokok Enfeksiyonu İle İlişkili Pediatrik Otoimmün Nöropsikiyatrik Hastalıklar: Kulak Burun Boğaz Hekiminin Yeri

Emrah KARA
Süleyman ÖZDEMİR
Pages
56–66
Publication Date
2014-11-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article, the treatment methods of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and the role of otolaryngologist were discussed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, refers to a disorder in children who manifest symptoms of obsessive-compulsive disorder and/or tic disorders associated with acute exacerbations.
📊
Key Findings & Data:Although autoimmune responses following infections with streptococcus have been hypothesized to be responsible, there is still controversies about the pathophysiology and treatment.
💡
Conclusion & Impact:In this article, the treatment methods of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and the role of otolaryngologist were discussed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:PANDAS · tedavi · tonsillektomi

Abstract

Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, refers to a disorder in children who manifest symptoms of obsessive-compulsive disorder and/or tic disorders associated with acute exacerbations. Although autoimmune responses following infections with streptococcus have been hypothesized to be responsible, there is still controversies about the pathophysiology and treatment. In this article, the treatment methods of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and the role of otolaryngologist were discussed.

Özet

Streptokok enfeksiyonu ile ilişkili pediatrik otoimmün nöropsikiyatrik hastalıklar, akut alevlenmelerle seyreden ve etkilenen çocuklarda obsesif kompulsif bozukluklar ve/veya tiklerle seyreden bir hastalıktır. Streptokok enfeksiyonu sonrası oluşan otoimmün yanıtın hastalıktan sorumlu olduğu düşünülse de, patofizyoloji ve tedavi üzerindeki tartışmalar halen devam etmektedir. Bu makalede, streptokok enfeksiyonu ile ilişkili pediatrik otoimmün nöropsikiyatrik hastalıkların tedavisi ve tedavide kulak burun boğaz hekiminin yeri tartışılacaktır.

🔖

Cite This Article

KARA, E., ÖZDEMİR, S. (2014). Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections: Role of Otolaryngologist. Arşiv Kaynak Tarama Dergisi, Cilt: 24 - Sayı: 1, 56–66. https://ajindex.com/articles/461976

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Swedo SE, Leonard HL, Garvey M, Mittleman B, Allen AJ, Perlmutter S et al. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: Clinical description of the first 50 cases. Am J Psychiatry. 1998;155:264–71.
  2. Kondo K, Kabasawa T. Improvement in Gilles de la Tourette syndrome after corticosteroid therapy. Ann Neurol. 1978;4:387. Darrow DH: Infectious and inflammatory illness of the oral cavity and pharynx. InTextbook Pediatric Otorhinolaryngology Head and Neck Surgery (Eds. CSouza, J Stankiewicz, PK Pellitteri):61-86.
  3. San Diego, Singular Pub, 1999.
  4. Wiatrak BJ, Woolley AL. Pharyngitis and adenotonsillar disease. In Pediatric Otolaryngology 4th edition (Ed CW Cummings). Philadelphia, Elsevier, 2005.
  5. Krober MS, Bass JW, Michels GN. Streptococcal pharyngitis: placebo-controlled double-blind evaluation of clinical response to penicillin therapy. JAMA. 1985;253:1271-74. Marshall T. A review of tonsillectomy for recurrent throat infection. Br J Gen Pract. 1998;48:1331- 5. Mouton Y.,Senneville E. Broad-versus narrow-spectrum antibiotic use - the role in vitro testing and its correlation with clinical efficacy. Postgrad Med J. 1992;68: 68-72.
  6. Peterson BS, Leckman JF, Tucker D, Scahill L, Staib L, Zhang H et al. Preliminary findings of antistreptococcal antibody titers and basal ganglia volumes in tic, obsessive-compulsive, and attention deficit/hyperactivity disorders. Arch Gen Psychiatry. 2000;57:364–72.
  7. Dale RC, Heyman I, Giovannoni G, Church AW: Incidence of antibrain antibodies in children with obsessive-compulsive disorder. Br J Psychiatry. 2005;187:314–9.
  8. Elia J, Dell ML, Friedman DF, Zimmerman RA, Balamuth N, Ahmed AA et al. PANDAS with catatonia: A case report. Therapeutic response to lorazepam and plasmapheresis. J Am Acad Child Adolesc Psychiatry. 2005;44:1145–50.
  9. Yaddanapudi K, Hornig M, Serge R, De Miranda J, Baghban A, Villar G et al. Passive transfer of streptococcus-induced antibodies reproduces behavioral disturbances in a mouse model of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection. Mol Psychiatry. 2010;15:712–26.
  10. Gause C, Morris C, Vernekar S, Pardo-Villamizar C, Grados MA, Singer HS. Antineuronal antibodies in OCD: comparisons in children with OCD-only, OCD+chronic tics and OCD+PANDAS. J Neuroimmunol. 2009;214:118–24.
  11. Morris CM, Pardo-Villamizar C, Gause CD, Singer HS. Serum auto antibodies measured by immunofluorescence confirm a failure to differentiate PANDAS and Toure