Journals / Balkan Medical Journal / 2013 / Cilt: 30 - Sayı: 1

Dosimetric evaluation of intensity modulated radiotherapy and 4-field 3-d conformal radiotherapy in prostate cancer treatment

Pages
54–57
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Dose-comparative evaluation of two techniques revealed the superiority of IMRT technique with statistically significantly lower femoral head doses along with reduced critical organ dose-volume parameters of bladder V60 (the volume receiving 60 Gy) and rectal V40 (the volume receiving 40 Gy) and V60.Conclusion: It can be concluded that IMRT is an effective definitive management tool for prostate cancer with improved critical organ sparing and excel- lent dose homogenization in target organs of prostate and seminal vesicles.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The purpose of this dosimetric study is the targeted dose homogeneity and critical organ dose comparison of 7-field Intensity Modulated Radiotherapy (IMRT) and 3-D 4-field conformal radiotherapy.
📊
Key Findings & Data:Material and Methods: Twenty patients with low and moderate risk prostate cancer treated at Gülhane Military Medical School Radiation Oncology Department between January 2009 and December 2009 are included in this study.
💡
Conclusion & Impact:Results: Dose-comparative evaluation of two techniques revealed the superiority of IMRT technique with statistically significantly lower femoral head doses along with reduced critical organ dose-volume parameters of bladder V60 (the volume receiving 60 Gy) and rectal V40 (the volume receiving 40 Gy) and V60.Conclusion: It can be concluded that IMRT is an effective definitive management tool for prostate cancer with improved critical organ sparing and excel- lent dose homogenization in target organs of prostate and seminal vesicles.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The purpose of this dosimetric study is the targeted dose homogeneity and critical organ dose comparison of 7-field Intensity Modulated Radiotherapy (IMRT) and 3-D 4-field conformal radiotherapy. Study Design: Cross sectional study. Material and Methods: Twenty patients with low and moderate risk prostate cancer treated at Gülhane Military Medical School Radiation Oncology Department between January 2009 and December 2009 are included in this study. Two seperate dosimetric plans both for 7-field IMRT and 3D-CRT have been generated for each patient to comparatively evaluate the dosimetric status of both techniques and all the patients received 7-field IMRT. Results: Dose-comparative evaluation of two techniques revealed the superiority of IMRT technique with statistically significantly lower femoral head doses along with reduced critical organ dose-volume parameters of bladder V60 (the volume receiving 60 Gy) and rectal V40 (the volume receiving 40 Gy) and V60.Conclusion: It can be concluded that IMRT is an effective definitive management tool for prostate cancer with improved critical organ sparing and excel- lent dose homogenization in target organs of prostate and seminal vesicles.

🔖

Cite This Article

DİNÇOĞLAN, F., SAGER, Ö., BEYZADEOĞLU, M., DEMİRAL, S., SÜRENKÖK, S., OYSUL, K., UYSAL, B., GAMSIZ, H. (2022). Dosimetric evaluation of intensity modulated radiotherapy and 4-field 3-d conformal radiotherapy in prostate cancer treatment. Balkan Medical Journal, Cilt: 30 - Sayı: 1, 54–57. https://ajindex.com/articles/461603

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (2)

  1. Beyzadeoğlu M, Ozyigit G, Ebruli C, editors. Basic Radiation Oncology. Berlin:Springer;2008. p.363-385
  2. Hanks GE, Leibel SA, Kral JM. Patterns of care studies:dose- response observations for local control of adenocarcinoma of the prostate. Int J Radiat Oncol Biol Phys 1985;11:153-7. [CrossRef] 3. Hanks GE, Martz KL, Diamond JJ. The effect of dose on local control of prostate cancer. Int J Radiat Oncol Biol Phys 1988;15:1299-305. [CrossRef] 4. Sandler HM, Perez-Tamayo C, Ten Haken RK. Dose escalation for stage C (T3) prostate cancer:minimal toxicity observed using conformal therapy. Radiother Oncol 1992;23:53-4. [CrossRef] 5. Hanks GE, Hanlon AL, Schultheiss TE. Dose escalation with 3D conformal treatment:five year outcomes, treatment optimization, and future directions. Int J Radiat Oncol Biol Phys 1998;41:501-10. [CrossRef] 6. Zelefsky MJ, Leibel SA, Gaudin PB. Dose escalation with three- dimensional conformal radiation therapy affects the outcome in prostate cancer. Int J Radiat Oncol Biol Phys 1998;41:491-500. [CrossRef] 7. Michalski JM, Purdy JA, Winter K. Preliminary report of toxicity following 3D radiation therapy for prostate cancer on 3DOG/ RTOG 94-06. Int J Radiat Oncol Biol Phys 2000;46:391-402. [CrossRef] 8. Ryu JK, Winter K, Michalski JM. Interim report of toxicity from 3D conformal radiation therapy (3D-CRT) for prostate cancer on 3DOG/RTOG 9406, level III (79.2 Gy). Int J Radiat Oncol Biol Phys 2002;54:1036-46. [CrossRef] 9. Luxton G, Hancock SL, Boyer AL. Dosimetry and radiobiologic model comparison of IMRT and 3D conformal radiotherapy in treatment of carcinoma of the prostate. Int J Radiat Oncol Biol Phys 2004;59:267-84. [CrossRef] 10. Latorzeff I, Mazurier J, Boutry C, Duodet P, Richaud P, Crovesier R. Benefit of intensity modulated and image-guided radiotherapy in prostate cancer. Cancer Radiother 2010;14:479-87. [CrossRef] 11. Zelefsky M, Fuksa Z, Happersett L, Leea H, Lingb C, Burman C, et al. Clinical experience with intensity modulated radiation therapy (IMRT) in prostate cancer. Radiother Oncol 2000;55:241- 9. [CrossRef] 12. Lee CT, Dong L, Ahamad AW, Choi H, Cheung R, Lee AK, et al. Comparison of treatment volumes and techniques in prostate cancer radiation therapy. Am J Clin Oncol 2005;28:618-25. [CrossRef] 13. Zhu S, Mizowaki T, Nagata Y, Takayama K, Norihisa Y, Yo S, et al. Comparison of three radiotherapy treatment planning protocols of definitive external-beam radiation for localized prostate cancer. Int J Clin Oncol 20